| severe respiratory illness associated with enterovirus d68 - missouri and illinois, 2014. | on august 19, 2014, cdc was notified by children's mercy hospital in kansas city, missouri, of an increase (relative to the same period in previous years) in patients examined and hospitalized with severe respiratory illness, including some admitted to the pediatric intensive care unit. an increase also was noted in detections of rhinovirus/enterovirus by a multiplex polymerase chain reaction assay in nasopharyngeal specimens obtained during august 5-19. on august 23, cdc was notified by the uni ... | 2014 | 25211545 |
| influx of patients with asthma-like symptoms strains resources in many pediatric eds. | an outbreak of a rarely seen virus in the united states is spiking volumes at pediatric eds across the country, with children typically presenting with asthma-like symptoms. cases of enterovirus d68 (ev-d68) first emerged in the midwest in early august, but the virus has since been confirmed in at least 40 states. the cdc is also investigating whether a cluster of nine pediatric cases involving young patients with muscle weakness or paralysis are related to the ev-d68 outbreak. the patients are ... | 2014 | 25362749 |
| enterovirus d68. a focused review and clinical highlights from the 2014 u.s. outbreak. | enterovirus d68 (ev-d68), a member of the picornaviridae family, was first identified in 1962 and is part of a group of small, nonenveloped rna viruses. as a family, these viruses are among the most common causes of disease among humans. however, outbreaks of disease attributable to ev-d68 have been rarely reported in the previous 4 decades. reports from a few localized outbreaks since 2008 describe severe lower respiratory tract infection in children. in the late summer of 2014, ev-d68 caused a ... | 2015 | 25714788 |
| epidemiology of enterovirus d68 in ontario. | in august 2014, children's hospitals in kansas city, missouri and chicago, illinois notified the centers for disease control and prevention (cdc) about increased numbers of pediatric patients hospitalized with severe respiratory illness (sri). in response to cdc reports, public health ontario laboratories (phol) launched an investigation of patients being tested for enterovirus d-68 (ev-d68) in ontario, canada. the purpose of this investigation was to enhance our understanding of ev-d68 epidemio ... | 2015 | 26599365 |
| molecular evolution and intraclade recombination of enterovirus d68 during the 2014 outbreak in the united states. | in august 2014, an outbreak of enterovirus d68 (ev-d68) occurred in north america, causing severe respiratory disease in children. due to a lack of complete genome sequence data, there is only a limited understanding of the molecular evolution and epidemiology of ev-d68 during this outbreak, and it is uncertain whether the differing clinical manifestations of ev-d68 infection are associated with specific viral lineages. we developed a high-throughput complete genome sequencing pipeline for ev-d6 ... | 2015 | 26656685 |