| association between toll-like receptor 2 (tlr2) polymorphisms and asymptomatic bancroftian filariasis. | lymphatic filariasis is mainly caused by the filarial nematodes wuchereria bancrofti and brugia malayi. wolbachia, intracellular symbiotic bacteria in filarial parasite, is known to induce immune response predominantly through toll-like receptor 2 (tlr2). this study was performed to investigate the association between polymorphisms of the tlr2 gene and susceptibility to asymptomatic bancroftian filariasis. a total of 142 unrelated asymptomatic bancroftian filariasis patients and 151 endemic norm ... | 2010 | 20549240 |
| a polymerase chain reaction assay for the survey of bancroftian filariasis. | a polymerase chain reaction (pcr) assay based on a highly repeated dna sequence found in wuchereria bancrofti (sspi repeat) has been modified for the survey of bancroftian filariasis in expatriate workers (myamese, karen and mon) from myanmar where human filariasis is endemic. the pcr was very sensitive with the ability to detect the presence of as little as 10 pg of parasite dna. the primers used in this pcr also showed highly specific amplification of parasite dna without the presence of non-s ... | 2002 | 12693583 |
| endemic bancroftian filariasis in thailand: detection by og4c3 antigen capture elisa and the polymerase chain reaction. | lymphatic filariasis, mainly caused by wuchereria bancrofti and brugia malayi, has been targeted for elimination by the world health organization by the year 2020. to achieve this goal, highly sensitive and specific diagnostic tests are necessary for close monitoring and evaluation of the control program. we employed an elisa to detect the og4c3 antigen and a polymerase chain reaction-based assay for diagnosis of w. bancrofti infection, among the thai-karen population in tak province, thailand. ... | 2001 | 11800304 |
| field trial of the ict filariasis for diagnosis of wuchereria bancrofti infections in an endemic population of thailand. | the ict filariasis, a rapid card test format, which is based on qualitative detection by monoclonal antibody of the circulating antigen of wuchereria bancrofti adult worm, is a new diagnostic test of choice for determining the infections under field conditions. by using clinical and recall techniques and microscopy (thick smear and capillary tube technique) as reference, we assessed the efficiency of the ict card test in sera from 225 subjects living in w. bancrofti-endemic villages of tak provi ... | 1999 | 10774670 |