infectious diseases epidemic threats and mass gatherings: refocusing global attention on the continuing spread of the middle east respiratory syndrome coronavirus (mers-cov). | media and world health organization (who) attention on zika virus transmission at the 2016 rio olympic games and the 2015 ebola virus outbreak in west africa diverted the attention of global public health authorities from other lethal infectious diseases with epidemic potential. mass gatherings such as the annual hajj pilgrimage hosted by kingdom of saudi arabia attract huge crowds from all continents, creating high-risk conditions for the rapid global spread of infectious diseases. the highly l ... | 2016 | 27604081 |
an outbreak of middle east respiratory syndrome (mers) due to coronavirus in al-ahssa region, saudi arabia, 2015. | between 19 april and 23 june 2015, 52 laboratory-confirmed cases of middle east respiratory syndrome due to coronavirus (mers) were reported from al-ahssa region, eastern saudi arabia. the first seven cases occurred in one family; these were followed by 45 cases in three public hospitals. the objectives of this investigation were to describe the epidemiological characteristic of the cluster and identify potential risk factors and control measures to be instituted to prevent further occurrence of ... | 2016 | 27714741 |
a phylogenetically distinct middle east respiratory syndrome coronavirus detected in a dromedary calf from a closed dairy herd in dubai with rising seroprevalence with age. | middle east respiratory syndrome coronavirus (mers-cov) was detected by monoclonal antibody-based nucleocapsid protein-capture enzyme-linked immunosorbent assay (elisa), rna detection, and viral culture from the nasal sample of a 1-month-old dromedary calf in dubai with sudden death. whole genome phylogeny showed that this mers-cov strain did not cluster with the other mers-cov strains from dubai that we reported recently. instead, it formed a unique branch more closely related to other mers-cov ... | 2015 | 26632876 |
lack of mers coronavirus neutralizing antibodies in humans, eastern province, saudi arabia. | we used a lentiviral vector bearing the viral spike protein to detect neutralizing antibodies against middle east respiratory syndrome coronavirus (mers-cov) in persons from the eastern province of saudi arabia. none of the 268 samples tested displayed neutralizing activity, which suggests that mers-cov infections in humans are infrequent in this province. | 2013 | 24274664 |
treatment outcomes for patients with middle eastern respiratory syndrome coronavirus (mers cov) infection at a coronavirus referral center in the kingdom of saudi arabia. | middle eastern respiratory syndrome coronavirus (mers-cov) is a poorly understood disease with no known treatments. we describe the clinical features and treatment outcomes of patients with laboratory confirmed mers-cov at a regional referral center in the kingdom of saudi arabia. | 2016 | 27097824 |
middle eastern respiratory syndrome corona virus (mers cov): case reports from a tertiary care hospital in saudi arabia. | middle eastern respiratory syndrome caused by novel coronavirus (mers cov) has been a major public health challenge since it was first described in 2012 in saudi arabia. so far, there is no effective treatment for this serious illness, which features a high mortality rate. we report an initial experience of the use of ribavirin and interferon (ifn)-a2b in the management of mers cov at a tertiary care hospital. | 2016 | 25827696 |