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toward developing a preventive mers-cov vaccine-report from a workshop organized by the saudi arabia ministry of health and the international vaccine institute, riyadh, saudi arabia, november 14-15, 2015.middle east respiratory syndrome (mers) remains a serious international public health threat. with the goal of accelerating the development of countermeasures against mers coronavirus (mers-cov), funding agencies, nongovernmental organizations, and researchers across the world assembled in riyadh, saudi arabia, on november 14-15, 2015, to discuss vaccine development challenges. the meeting was spearheaded by the saudi ministry of health and co-organized by the international vaccine institute, so ...201627439020
acute viral respiratory infections among children in mers-endemic riyadh, saudi arabia, 2012-2013.the emergence of the middle east respiratory syndrome (mers) in saudi arabia has intensified focus on acute respiratory infections [aris]. this study sought to identify respiratory viruses (rvs) associated with aris in children presenting at a tertiary hospital. children (aged ≤13) presenting with ari between january 2012 and december 2013 tested for 15 rvs using the seeplex(r) rv15 kit were retrospectively included. epidemiological data was retrieved from patient records. of the 2235 children t ...201727430485
middle east respiratory syndrome (mers) coronavirus seroprevalence in domestic livestock in saudi arabia, 2010 to 2013.in saudi arabia, including regions of riyadh and al ahsa, pseudoparticle neutralisation (ppnt) and microneutralisation (mnt) tests detected no antibodies to middle east respiratory syndrome coronavirus (mers-cov) in sheep (n= 100), goats (n= 45), cattle (n= 50) and chickens (n= 240). dromedary camels however, had a high prevalence of mers-cov antibodies. bovine coronavirus (bcov) infected sera from cattle had no cross-reactivity in mers-cov ppnt or mnt, while many dromedary camels’ sera reacted ...201324342517
variations in spike glycoprotein gene of mers-cov, south korea, 2015.an outbreak of nosocomial infections with middle east respiratory syndrome coronavirus occurred in south korea in may 2015. spike glycoprotein genes of virus strains from south korea were closely related to those of strains from riyadh, saudi arabia. however, virus strains from south korea showed strain-specific variations.201626691200
notes from the field: nosocomial outbreak of middle east respiratory syndrome in a large tertiary care hospital--riyadh, saudi arabia, 2015.since the first diagnosis of middle east respiratory syndrome (mers) caused by the mers coronavirus (mers-cov) in the kingdom of saudi arabia in 2012, sporadic cases and clusters have occurred throughout the country (1). during june-august, 2015, a large mers outbreak occurred at king abulaziz medical city, a 1,200-bed tertiary-care hospital that includes a 150-bed emergency department that registers 250,000 visits per year.201626890816
deletion variants of middle east respiratory syndrome coronavirus from humans, jordan, 2015.we characterized middle east respiratory syndrome coronaviruses from a hospital outbreak in jordan in 2015. the viruses from jordan were highly similar to isolates from riyadh, saudi arabia, except for deletions in open reading frames 4a and 3. transmissibility and pathogenicity of this strain remains to be determined.201626981770
proceedings of the middle east respiratory syndrome (mers) coronavirus research initiative workshop, september 9-10 2015 in riyadh, ksa. 201727036308
description of a hospital outbreak of middle east respiratory syndrome in a large tertiary care hospital in saudi arabia.background since the first isolation of middle east respiratory syndrome coronavirus (mers-cov) in saudi arabia in 2012, sporadic cases, clusters, and sometimes large outbreaks have been reported. objective to describe the recent (2015) mers-cov outbreak at a large tertiary care hospital in riyadh, saudi arabia. methods we conducted an epidemiologic outbreak investigation, including case finding and contact tracing and screening. mers-cov cases were categorized as suspected, probable, and confir ...201627426423
are saudi medical students aware of middle east respiratory syndrome coronavirus during an outbreak?recently, an outbreak of mers-cov occurred in king abdulaziz medical city (kamc), riyadh. this outbreak contributed to the students at the king saud bin abdulaziz university for health sciences (ksau-hs) becoming more involved in promoting health awareness in their communities. this was a cross-sectional study that evaluated students in the clinical phase of medical school. the data were collected by an online questionnaire. the measurements were obtained using a researcher-administered and a se ...201727502524
awareness, attitudes, and practices related to coronavirus pandemic among public in saudi arabia.new cases of middle east respiratory syndrome coronavirus (mers-cov) were reported in gulf countries in 2014, and to date, it has reportedly infected 837 people and killed 291 globally. awareness of an individual's knowledge and being able to predict his or her behavior is crucial when evaluating clinical preparedness for pandemics with a highly pathogenic virus. the aim of this study was to identify awareness, attitudes, and practices related to mers-cov among the public in saudi arabia. a cros ...201526291193
an observational, laboratory-based study of outbreaks of middle east respiratory syndrome coronavirus in jeddah and riyadh, kingdom of saudi arabia, 2014.in spring 2014, a sudden rise in the number of notified middle east respiratory syndrome coronavirus (mers-cov) infections occurred across saudi arabia with a focus in jeddah. hypotheses to explain the outbreak pattern include increased surveillance, increased zoonotic transmission, nosocomial transmission, and changes in viral transmissibility, as well as diagnostic laboratory artifacts.201525323704
middle east respiratory syndrome corona virus, mers-cov. conclusions from the 2nd scientific advisory board meeting of the who collaborating center for mass gathering medicine, riyadh. 201424818990
dynamics of scientific publications on the mers-cov outbreaks in saudi arabia.middle east respiratory syndrome coronavirus (mers-cov) is an emerging disease with a relatively high case fatality rate. most cases have been reported from saudi arabia, and the disease epidemic potential is considered to be limited. however, human-human transmission has occurred, usually in the context of healthcare facility-associated outbreaks. the scientific and medical community depends on timely publication of epidemiological information on emerging diseases during outbreaks to appropriat ...201728625842
mers-cov infection: mind the public knowledge gap.in august 2015, the corona outbreak caused by middle east respiratory syndrome coronavirus (mers-cov) was the 9th episode since june 2012 in saudi arabia. little is known about the public awareness toward the nature or prevention of the disease. the aim of this work was to assess the knowledge of the adult population in riyadh toward the mers-cov. in this cross-sectional survey, a self-administrated questionnaire was distributed to randomly selected participants visiting malls in riyadh. the que ...201728647126
identification of information types and sources by the public for promoting awareness of middle east respiratory syndrome coronavirus in saudi arabia.middle east respiratory syndrome (mers) is a viral respiratory disease of serious consequences caused by mers coronavirus (mers-cov). saudi communities still lack awareness of available protective measures to prevent the transmission of the virus. it is necessary to explore the current information-seeking strategies and preferences for communication tools among the saudi population to promote dissemination of accurate information. guided by mcguire's input-output persuasion model and focusing on ...201626612051
molecular epidemiology of hospital outbreak of middle east respiratory syndrome, riyadh, saudi arabia, 2014.we investigated an outbreak of middle east respiratory syndrome (mers) at king fahad medical city (kfmc), riyadh, saudi arabia, during march 29-may 21, 2014. this outbreak involved 45 patients: 8 infected outside kfmc, 13 long-term patients at kfmc, 23 health care workers, and 1 who had an indeterminate source of infection. sequences of full-length mers coronavirus (mers-cov) from 10 patients and a partial sequence of mers-cov from another patient, when compared with other mers-cov sequences, de ...201526484549
host-directed therapies for improving poor treatment outcomes associated with the middle east respiratory syndrome coronavirus infections.three years after its first discovery in jeddah saudi arabia, the novel zoonotic pathogen of humans, the middle east respiratory syndrome coronavirus (mers-cov) continues to be a major threat to global health security.(1) sporadic community acquired cases of mers continue to be reported from the middle east. the recent nosocomial outbreaks in hospitals in seoul, korea and at the national guard hospital in riyadh, saudi arabia indicate the epidemic potential of mers-cov. currently there are no ef ...201526365771
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