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long-term colonization of the cystic fibrosis lung by burkholderia cepacia complex bacteria: epidemiology, clonal variation, and genome-wide expression alterations.long-term respiratory infections with burkholderia cepacia complex (bcc) bacteria in cystic fibrosis (cf) patients generally lead to a more rapid decline in lung function and, in some cases, to a fatal necrotizing pneumonia known as the "cepacia syndrome." bcc bacteria are ubiquitous in the environment and are recognized as serious opportunistic pathogens that are virtually impossible to eradicate from the cf lung, posing a serious clinical threat. the epidemiological survey of bcc bacteria invo ...201122919578
incidence of burkholderia contaminans at a cystic fibrosis centre with an unusually high representation of burkholderia cepacia during 15 years of epidemiological surveillance.the burkholderia cepacia complex (bcc) is a heterogeneous group of bacteria comprising around 20 related species. these bacteria are important opportunistic pathogens, especially in cystic fibrosis (cf) patients, and are associated with a worse prognosis and decreased life expectancy. the taxonomic position of 20 bcc isolates retrieved from cf patients receiving care at hospital santa maria (hsm), in lisbon, from 1995 to 2006, was re-examined in the present work. these isolates, formerly classif ...201526002942
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