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protection of peruvian children against rotavirus diarrhea of specific serotypes by one, two, or three doses of the rit 4237 attenuated bovine rotavirus vaccine.a randomized placebo-controlled double-blind field trial of rit 4237 attenuated rotavirus vaccine in lima, peru, evaluated the protection against diarrheal illness by one, two, or three doses of vaccine. there were 391 children, 2-18 months old, studied for the occurrence of diarrhea during the 18 months after vaccination. three doses of the vaccine provided 40% protection against any diarrheal illness associated with rotavirus alone but 58%-75%; protection against the more severe rotaviral illn ...19892536789
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