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circulating serotypes of dengue virus and their incursion into non-endemic areas of pakistan; a serious threat.dengue virus is circulating in pakistan since 1994, which causes major and minor outbreaks in many areas of the country. the incidence of dengue in pakistan in past years mainly restricted to parts of sindh and punjab provinces. as such, a severe dengue outbreak appeared in pakistan in 2011, particularly in punjab province with lahore as the most hit city (290 deaths). in 2013, for the first time in the history of pakistan, dengue outbreak erupted in swat district, khyber pakhtunkhwa, which clai ...201627565893
a comprehensive entomological, serological and molecular study of 2013 dengue outbreak of swat, khyber pakhtunkhwa, pakistan.aedes aegypti and aedes albopictus play a fundamental role in transmission of dengue virus to humans. a single infected aedes mosquito is capable to act as a reservoir/amplifier host for dengue virus and may cause epidemics via horizontal and vertical modes of dengue virus (denv) transmission. the present and future dengue development can be clarified by understanding the elements which help the dissemination of dengue transmission. the current study deals with molecular surveillance of dengue i ...201626848847
dengue epidemic in postconflict swat district, khyber pakhtunkhwa, pakistan, 2013.abstractswat, a lush green valley of 1.3 million persons, remained under militant insurgency from 2007 to 2009, which damaged the health infrastructure. an outbreak of dengue fever (df) was declared in the valley in 2013. to investigate this outbreak, we established active surveillance of national hospitals and private clinics, reviewed available clinical and laboratory records, and conducted entomological survey. from august to november 2013, 16,000 suspected patients with acute febrile illness ...201728093537
dengue virus serotypes circulating in khyber pakhtunkhwa province, pakistan, 2013-2015.from 2013 to 2015, the national institute of health, pakistan, received 1,270 blood samples of suspected dengue cases reported from inpatient and outpatient departments of various hospitals in khyber pakhtunkhwa (kpk) province. in this study, we determined the circulating dengue virus (denv) serotypes using real-time reverse transcriptase (rt)-pcr to understand the serotype-based epidemiology of denv. all four serotypes (denv-1 [6%], denv-2 [33%], denv-3 [47%], and denv-4 [0.1%]) were found circ ...201728029002
outbreak of dengue virus type-3 in malakand, pakistan 2015; a laboratory perspective.an outbreak of dengue fever was reported in malakand district, khyber pakhtunkhwa (kp) province of pakistan during 2015. detection of viral rna by real-time pcr confirmed dengue virus serotype-3 (denv-3) to be the causative agent causing the outbreak. phylogenetic analysis based on partial e-ns1 gene sequences showed that the denv-3 viruses belonged to genotype iii with maximum homology with the dengue-3 strains previously reported from pakistan and india. our current report provides updated inf ...201728219668
demographic characteristics of dengue virus outbreaks in khyber pakhtunkhwa province, pakistan during 2003-2015. 201728291567
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