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rapid selection of plasmodium falciparum chloroquine resistance transporter gene and multidrug resistance gene-1 haplotypes associated with past chloroquine and present artemether-lumefantrine use in inhambane district, southern mozambique.chloroquine (cq) use in mozambique was stopped in 2002 and artemether-lumefantrine (al) was implemented in 2008. in light of no use of cq and extensive use of al, we determined the frequency of molecular markers of plasmodium falciparum drug resistance/tolerance to cq and al in persons living in linga-linga, an isolated peninsula and in furvela village, which is located 8 km inland. the p. falciparum chloroquine resistance transporter gene cvmnk wild type increased in frequency from 43.9% in 200 ...201323382159
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