| clinical observations in 42 patients with lassa fever. | under continuous observation of several months, 42 patients from the eastern province of sierra leone, liberia (lofa county), and neighbouring guinea were identified as lassa fever cases by indirect immunofluorescent antibody technique, indicating that the disease is endemic in these areas. the clinical course varied from mild disease to severe illness with haemorrhagic disorders. the fatality rate was 14%. the occurrence of only two possible secondary cases suggests that person-to-person spread ... | 1980 | 7233535 |
| effect of artesunate-amodiaquine on mortality related to ebola virus disease. | malaria treatment is recommended for patients with suspected ebola virus disease (evd) in west africa, whether systeomatically or based on confirmed malaria diagnosis. at the ebola treatment center in foya, lofa county, liberia, the supply of artemether-lumefantrine, a first-line antimalarial combination drug, ran out for a 12-day period in august 2014. during this time, patients received the combination drug artesunate-amodiaquine; amodiaquine is a compound with anti-ebola virus activity in vit ... | 2016 | 26735991 |
| community attitudes toward mass drug administration for control and elimination of neglected tropical diseases after the 2014 outbreak of ebola virus disease in lofa county, liberia. | the recent outbreak of ebola virus disease (evd) interrupted mass drug administration (mda) programs to control and eliminate neglected tropical diseases in liberia. mda programs treat entire communities with medication regardless of infection status to interrupt transmission and eliminate lymphatic filariasis and onchocerciasis. following reports of hostilities toward health workers and fear that they might be spreading evd, it was important to determine whether attitudes toward mda might have ... | 2016 | 26666700 |
| social vulnerability and ebola virus disease in rural liberia. | the ebola virus disease (evd) epidemic that has stricken thousands of people in the three west african countries of liberia, sierra leone, and guinea highlights the lack of adaptive capacity in post-conflict countries. the scarcity of health services in particular renders these populations vulnerable to multiple interacting stressors including food insecurity, climate change, and the cascading effects of disease epidemics such as evd. however, the spatial distribution of vulnerable rural populat ... | 2015 | 26325519 |
| challenges in responding to the ebola epidemic - four rural counties, liberia, august-november 2014. | the first cases of ebola virus disease (ebola) in west africa were identified in guinea on march 22, 2014. on march 30, the first liberian case was identified in foya town, lofa county, near the guinean border. because the majority of early cases occurred in lofa and montserrado counties, resources were concentrated in these counties during the first several months of the response, and these counties have seen signs of successful disease control. by october 2014, the epidemic had reached all 15 ... | 2014 | 25522089 |
| evidence for a decrease in transmission of ebola virus--lofa county, liberia, june 8-november 1, 2014. | lofa county has one of the highest cumulative incidences of ebola virus disease (ebola) in liberia. recent situation reports from the liberian ministry of health and social welfare (mohsw) have indicated a decrease in new cases of ebola in lofa county. in october 2014, the liberian mohsw requested the assistance of cdc to further characterize recent trends in ebola in lofa county. data collected during june 8-november 1, 2014 from three sources were analyzed: 1) aggregate data for newly reported ... | 2014 | 25412065 |
| control of ebola virus disease - firestone district, liberia, 2014. | on march 30, 2014, the ministry of health and social welfare (mohsw) of liberia alerted health officials at firestone liberia, inc. (firestone) of the first known case of ebola virus disease (ebola) inside the firestone rubber tree plantation of liberia. the patient, who was the wife of a firestone employee, had cared for a family member with confirmed ebola in lofa county, the epicenter of the ebola outbreak in liberia during march-april 2014. to prevent a large outbreak among firestone's 8,500 ... | 2014 | 25340914 |
| assessment of ebola virus disease, health care infrastructure, and preparedness - four counties,southeastern liberia, august 2014. | ebola virus disease (ebola) is a multisystem disease caused by a virus of the genus ebolavirus. in late march 2014, ebola cases were described in liberia, with epicenters in lofa county and later in montserrado county. while information about case burden and health care infrastructure was available for the two epicenters, little information was available about remote counties in southeastern liberia. over 9 days, august 6-14, 2014, ebola case burden, health care infrastructure, and emergency pre ... | 2014 | 25299605 |
| community-led total sanitation, open defecation free status, and ebola virus disease in lofa county, liberia. | the ebola virus disease (evd) epidemic entered liberia through lofa county in february 2014 and spread to two health districts where the nongovernmental organization global communities had been implementing community-led total sanitation (clts) since 2012. by december 2014 the county had 928 ebola cases (422 of them confirmed) and 648 deaths. before the epidemic, clts was triggered in 155 communities, and 98 communities were certified as open defecation free (odf). using mixed quantitative and q ... | 2017 | 28854135 |
| the impact of control strategies and behavioural changes on the elimination of ebola from lofa county, liberia. | the ebola epidemic in west africa was stopped by an enormous concerted effort of local communities and national and international organizations. it is not clear, however, how much the public health response and behavioural changes in affected communities, respectively, contributed to ending the outbreak. here, we analyse the epidemic in lofa county, liberia, lasting from march to november 2014, by reporting a comprehensive time line of events and estimating the time-varying transmission intensit ... | 2017 | 28396473 |