| registry of 919 patients with thrombotic microangiopathies across japan: database of nara medical university during 1998-2008. | thrombotic microangiopathies (tmas) are pathological conditions characterized by generalized microvascular occlusion by platelet thrombi, thrombocytopenia, and microangiopathic hemolytic anemia. two typical phenotypes of tmas are hemolytic-uremic syndrome (hus) and thrombotic thrombocytopenic purpura (ttp). severe deficiency of plasma adamts13 activity (adamts13: ac) is more specific for ttp, but not for hus. since 1998, our laboratory has functioned as a nationwide referral center for tmas by a ... | 2010 | 20045995 |