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genetic diversity of coxsackievirus a16 associated with hand, foot, and mouth disease epidemics in japan from 1983 to 2003.to clarify the chronologic genetic diversity of coxsackievirus a16 (cv-a16) strains associated with hand, foot, and mouth disease (hfmd) epidemics in a restricted area and their genetic relation with those isolated in other areas, we investigated the genetic diversity of the 129 cv-a16 strains associated with hfmd epidemics in fukushima, japan, from 1983 to 2003, and compared their genetic relation to 49 cv-a16 strains isolated in other areas of japan and in china by using phylogenetic analysis ...200717093028
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