| development and evaluation of a real-time one step reverse-transcriptase pcr for quantitation of chandipura virus. | chandipura virus (chpv), a member of family rhabdoviridae was attributed to an explosive outbreak of acute encephalitis in children in andhra pradesh, india in 2003 and a small outbreak among tribal children from gujarat, western india in 2004. the case-fatality rate ranged from 55-75%. considering the rapid progression of the disease and high mortality, a highly sensitive method for quantifying chpv rna by real-time one step reverse transcriptase pcr (real-time one step rt-pcr) using taqman tec ... | 2008 | 19091082 |
| changing clinical scenario in chandipura virus infection. | chandipura virus (chpv) (vesiculovirus: rhabdoviridae) garnered global attention as an emerging neurotropic pathogen inflicting high mortality in children within 24 h of commencement of symptoms. the 2003-2004 outbreaks in central india witnessed case fatality rates ranging from 56-75 per cent in andhra pradesh and gujarat with typical encephalitic symptoms. due to the acute sickness and rapid deterioration, the precise mechanism of action of the virus is still unknown. recent studies have shown ... | 0 | 27748295 |
| genetic characterization of the glycoprotein g of chandipura viruses in india with emphasis on an outbreak of 2015. | chandipura virus (chpv) is found to be associated with sporadic encephalitis outbreaks in humans in india since 1965. we report here, the investigation of chpv activity during the period of june-august 2015 in the state of gujarat, which revealed 24.44% positivity among 45 referred encephalitis cases. phylogenetic study of the g gene sequences of strains from gujarat 2015 along with available sequences of additional strains from different geographical locations and isolation years (1965-2015), i ... | 2017 | 28882516 |