| malaria vector populations across ecological zones in guinea conakry and mali, west africa. | malaria remains a pervasive public health problem in sub-saharan west africa. here mosquito vector populations were explored across four sites in mali and the republic of guinea (guinea conakry). the study samples the major ecological zones of malaria-endemic regions in west africa within a relatively small distance. | 2016 | 27059057 |
| depressive symptoms among survivors of ebola virus disease in conakry (guinea): preliminary results of the postebogui cohort. | the 2013-2016 west african ebola outbreak infected 28,616 people and caused 11,310 deaths by 11 may 2016, across six countries. the outbreak has also resulted in the largest number of evd survivors in history-over 17,000. guinea was declared ebola-free on 1 june 2016. reports from the outbreak documented 3814 cases resulting in 2544 deaths and 1270 survivors. evd survivors face various neuropsychological and psycho-affective alterations that have not been fully identified yet. this study aims to ... | 2017 | 28376850 |
| aerial medical evacuation of health workers with suspected ebola virus disease in guinea conakry-interest of a negative pressure isolation pod-a case series. | we report 4 cases of health workers (hw) suspected of having contracted ebola virus disease (evd), transported from the alliance for international medical action (alima) ebola treatment centre (etc) in n'zerekore, guinea to the treatment centre for carers run by the medical corps of the french army in conakry, the capital of guinea, which was established on 17 january 2015 and closed on 7 july 2015. in total more than 500 hws have died from evd since the epidemic began. this mortality has had si ... | 2017 | 28284181 |
| [field assessment of the new rapid diagnostic test ebola ezyscreen®]. | during the ebola virus disease outbreak in west africa in 2014, the world health organization has pointed out the need for rapid diagnostic tests (rdt) affordable, sensitive, specific, user-friendly, rapid, equipment-free, and deliverable. the rapid diagnostic test (lateral flow assay) ebola ezyscreen® was developed in this emergency frame using monoclonal antibodies against the envelope glycoprotein of the virus. two distinct versions have been industrialized, one for whole-blood samples and th ... | 2017 | 28050868 |
| unusual ebola virus chain of transmission, conakry, guinea, 2014-2015. | in october 2015, a new case of ebola virus disease in guinea was detected. case investigation, serology, and whole-genome sequencing indicated possible transmission of the virus from an ebola virus disease survivor to another person and then to the case-patient reported here. this transmission chain over 11 months suggests slow ebola virus evolution. | 2016 | 27869596 |
| [ebola virus disease: clinical presentation, prognosis and treatment]. | the clinical spectrum of ebola virus disease (evd) ranges from very serious forms with organ failure and death within days to paucisymptomatic forms and perhaps even asymptomatic. the authors propose a focus on the clinical manifestations of evd, on prognosis and on therapeutic aspects (excluding resuscitation). this work extracts from the literature the main data gathered during the 2014-2015 epidemic that raged in guinea conakry and sierra leone. these two countries, even if they are separated ... | 2017 | 27717513 |
| [revival after ebola: multidisciplinary assessment at 1 year, prospect and follow-up study of surviving patients from ebola in guinea (postebogui cohort)]. | ebola virus disease (evd) epidemic that spread in west africa from the end of 2013 to early 2016 has reached more people than all past epidemics. beyond care management of acute phase ill patients and measures for the control of the epidemic, the outcome of ebola survivors became an important question as their number increased and raised new issues. a multidisciplinary prospective cohort of survivors in guinea has been launched by ird umi 233 and donka national hospital, conakry, guinea, to asse ... | 2016 | 27704472 |
| [epidemiological aspects of ebola virus disease in guinea (december 2013-april 2016)]. | ebola zaire species variant makona between its emergence in december 2013 and april 2016, resulted in an epidemic of guinea importance and unprecedented gravity with 3814 reported cases of which 3358 were confirmed (88.0%) and 2544 were died (66.7%). the epidemic has evolved in phases: a silent phase without identification of all fatal cases until february 2014; a first outbreak from march 2014, when the alarm is raised and the virus detected, which lasted until july 2014; a second increase, whi ... | 2016 | 27456159 |
| [ebola in guinea: experience of stigma among health professional survivors]. | this article aims to describe the various forms of stigma faced by ebola health professional survivors. a study based on in-depth interviews with 20 survivors was conducted in conakry as part of postebogui multidisciplinary cohort research program (life after ebola) in july-august 2015. participants were health professionals, male and female, mostly with precarious positions in the health system. the results show that stigmatization is mainly expressed through avoidance, rejection, or being refu ... | 2016 | 27456158 |
| organizing the donation of convalescent plasma for a therapeutic clinical trial on ebola virus disease: the experience in guinea. | although convalescent plasma (cp) transfusion was prioritized among potential ebola treatments by the world health organization, there were concerns on the feasibility of its implementation. we report on the successful organization of donor mobilization and plasma collection as part of the ebola-tx clinical trial from november 2014 to july 2015 in conakry, guinea. project implementation registers, tools and reports, mission reports, and minutes of research team meetings were used to reconstruct ... | 2016 | 27430546 |
| evaluation of a national call center and a local alerts system for detection of new cases of ebola virus disease - guinea, 2014-2015. | the epidemic of ebola virus disease (ebola) in west africa began in guinea in late 2013 (1), and on august 8, 2014, the world health organization (who) declared the epidemic a public health emergency of international concern (2). guinea was declared ebola-free on december 29, 2015, and is under a 90 day period of enhanced surveillance, following 3,351 confirmed and 453 probable cases of ebola and 2,536 deaths (3). passive surveillance for ebola in guinea has been conducted principally through th ... | 2016 | 26963195 |
| ethnomedical and ethnobotanical investigations on the response capacities of guinean traditional health practioners in the management of outbreaks of infectious diseases: the case of the ebola virus epidemic. | the recent outbreak of ebola virus infections has mostly remained confined to the west african countries guinea-conakry, sierra-leone and liberia. due to intense national and international mobilizations, a significant reduction in ebola virus transmission has been recorded. while international efforts focus on new vaccines, medicines and diagnostics, no coherent national or international approach exists to integrate the potential of the traditional health practitioners (thps) in the management o ... | 2016 | 26900129 |
| misconceptions about ebola virus disease among lay people in guinea: lessons for community education. | to characterize the perception of ebola virus disease (evd) in guinea, we administered, from november 2014 to february 2015, a questionnaire to a convenience sample of 200 lay people in conakry and a group of 8 physicians. we found widespread misconceptions among lay people, including that praying to god can protect against evd, that traditional healers are more competent than physicians in treating evd, that people get infected through physical proximity without contact, that the ebola epidemic ... | 2016 | 26865320 |
| epidemiology of epidemic ebola virus disease in conakry and surrounding prefectures, guinea, 2014-2015. | in 2014, ebola virus disease (evd) in west africa was first reported during march in 3 southeastern prefectures in guinea; from there, the disease rapidly spread across west africa. we describe the epidemiology of evd cases reported in guinea's capital, conakry, and 4 surrounding prefectures (coyah, dubreka, forecariah, and kindia), encompassing a full year of the epidemic. a total of 1,355 evd cases, representing ≈40% of cases reported in guinea, originated from these areas. overall, forecariah ... | 2016 | 26812047 |
| moderate thermal strain in healthcare workers wearing personal protective equipment during treatment and care activities in the context of the 2014 ebola virus disease outbreak. | the extent of thermal strain while wearing personal protective equipment (ppe) during care activities for ebola virus disease patients has not yet been characterized. from january to march 2015, 25 french healthcare workers (hcws) in conakry, guinea, volunteered to be monitored while wearing ppe using an ingestible thermal sensor. the mean (standard deviation) working ambient temperature and relative humidity were 29.6 °c (2.0 °c) and 65.4% (10.3%), respectively; the mean time wearing ppe was 65 ... | 2016 | 26655297 |
| development and deployment of a rapid recombinase polymerase amplification ebola virus detection assay in guinea in 2015. | in the absence of a vaccine or specific treatments for ebola virus disease (evd), early identification of cases is crucial for the control of evd epidemics. we evaluated a new extraction kit (speedxtract (se), qiagen) on sera and swabs in combination with an improved diagnostic reverse transcription recombinase polymerase amplification assay for the detection of ebola virus (ebov-rt-rpa). the performance of combined extraction and detection was best for swabs. sensitivity and specificity of the ... | 2015 | 26558690 |
| the use of ebola convalescent plasma to treat ebola virus disease in resource-constrained settings: a perspective from the field. | the clinical evaluation of convalescent plasma (cp) for the treatment of ebola virus disease (evd) in the current outbreak, predominantly affecting guinea, sierra leone, and liberia, was prioritized by the world health organization in september 2014. in each of these countries, nonrandomized comparative clinical trials were initiated. the ebola-tx trial in conakry, guinea, enrolled 102 patients by 7 july 2015; no severe adverse reactions were noted. the ebola-cp trial in sierra leone and the evd ... | 2016 | 26261205 |
| distinct lineages of ebola virus in guinea during the 2014 west african epidemic. | an epidemic of ebola virus disease of unprecedented scale has been ongoing for more than a year in west africa. as of 29 april 2015, there have been 26,277 reported total cases (of which 14,895 have been laboratory confirmed) resulting in 10,899 deaths. the source of the outbreak was traced to the prefecture of guéckédou in the forested region of southeastern guinea. the virus later spread to the capital, conakry, and to the neighbouring countries of sierra leone, liberia, nigeria, senegal and m ... | 2015 | 26106863 |
| ebola transmission linked to a single traditional funeral ceremony - kissidougou, guinea, december, 2014-january 2015. | on december 18, 2014, the guinea ministry of health was notified by local public health authorities in kissidougou, a prefecture in southeastern guinea (pop. 284,000), that the number of cases of ebola virus disease (ebola) had increased from one case reported during december 8-14, 2014, to 62 cases reported during december 15-21. kissidougou is one of the four guinea prefectures (the others are macenta, gueckedou, and conakry) where ebola was first reported in west africa in march 2014, and the ... | 2015 | 25879897 |
| chains of transmission and control of ebola virus disease in conakry, guinea, in 2014: an observational study. | an epidemic of ebola virus disease of unprecedented size continues in parts of west africa. for the first time, large urban centres such as conakry, the capital of guinea, are affected. we did an observational study of patients with ebola virus disease in three regions of guinea, including conakry, aiming to map the routes of transmission and assess the effect of interventions. | 2015 | 25619149 |
| ebola outbreak in conakry, guinea: epidemiological, clinical, and outcome features. | the authors studied the epidemiological, clinical, and outcome features of the ebola virus disease in patients hospitalized at the ebola treatment center (etc) in conakry to identify clinical factors associated with death. | 2014 | 25391486 |
| clinical presentation of patients with ebola virus disease in conakry, guinea. | in march 2014, the world health organization was notified of an outbreak of zaire ebolavirus in a remote area of guinea. the outbreak then spread to the capital, conakry, and to neighboring countries and has subsequently become the largest epidemic of ebola virus disease (evd) to date. | 2015 | 25372658 |
| ebola viral disease outbreak--west africa, 2014. | on march 21, 2014, the guinea ministry of health reported the outbreak of an illness characterized by fever, severe diarrhea, vomiting, and a high case-fatality rate (59%) among 49 persons. specimens from 15 of 20 persons tested at institut pasteur in lyon, france, were positive for an ebola virus by polymerase chain reaction. viral sequencing identified ebola virus (species zaïre ebolavirus), one of five viruses in the genus ebolavirus, as the cause. cases of ebola viral disease (evd) were init ... | 2014 | 24964881 |
| occupational exposures to ebola virus in ebola treatment center, conakry, guinea. | we report 77 cases of occupational exposures for 57 healthcare workers at the ebola treatment center in conakry, guinea, during the ebola virus disease outbreak in 2014-2015. despite the high incidence of 3.5 occupational exposures/healthcare worker/year, only 18% of workers were at high risk for transmission, and no infections occurred. | 2017 | 28726614 |
| mortality among pcr negative admitted ebola suspects during the 2014/15 outbreak in conakry, guinea: a retrospective cohort study. | non-cases are suspect ebola virus disease (evd) cases testing negative by evd rt-pcr after admission to an ebola treatment centre (etc). admitting non-cases to an etc prompts concerns on case- and workload in the etc, risk for nosocomial evd infection, and delays in diagnosis and disease-specific treatment. we retrospectively analysed characteristics, outcomes and determinants of death of evd cases and non-cases admitted to the conakry etc in guinea between 03/2014 and 09/2015. of the 2362 admit ... | 2017 | 28665950 |
| vaccination and blood sampling acceptability during ramadan fasting month: a cross-sectional study in conakry, guinea. | there are few data on the acceptability of vaccination or blood sampling during ramadan fasting month in muslim countries. this could impact vaccination campaigns, clinical trials or healthcare during ramadan. | 2017 | 28385606 |
| upholding tuberculosis services during the 2014 ebola storm: an encouraging experience from conakry, guinea. | ten targeted health facilities supported by damien foundation (a belgian non governmental organization) and the national tuberculosis (tb) program in conakry, guinea. | 2016 | 27533499 |
| [global management of patients with ebola viral disease, experience of the healthcare workers treatment of conakry, guinea]. | the healthcare workers treatment center of conakry, guinea, was inaugurated in january 2015. it is dedicated to the diagnosis and the treatment of healthcare workers with probable or confirmed ebola viral disease. it is staffed by the french army medical service. the french military team may reconcile their medical practice and the ethno-cultural imperatives to optimise the patient adherence during his hospitalization. | 2016 | 26850104 |
| introduction of mobile health tools to support ebola surveillance and contact tracing in guinea. | challenges in data availability and quality have contributed to the longest and deadliest ebola epidemic in history that began in december 2013. accurate surveillance data, in particular, has been difficult to access, as it is often collected in remote communities. we describe the design, implementation, and challenges of implementing a smartphone-based contact tracing system that is linked to analytics and data visualization software as part of the ebola response in guinea. the system, built on ... | 2015 | 26681710 |
| [guinea: the army nurses caring for health workers infected with ebola]. | in the first half of 2015, army nurses from the french army, worked with the conakry health worker treatment centre in guinea. their aim was to save the lives of health workers risking their lives in the fight against the ebola epidemic. this article describes a mission which proved memorable both on a human and professional level. | 2015 | 26548391 |