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case fatality associated with a hypervirulent strain in patients with culture-positive clostridium difficile infection: a retrospective population-based study.clostridium difficile is a major infectious cause of healthcare-associated diarrhea. the epidemiology of c. difficile infection (cdi) is changing, with evidence of increased incidence and severity. the first patient with a hypervirulent strain type in pirkanmaa hospital district, finland was reported in september 2008.201222572612
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