| invited commentary: dengue lessons from cuba. | an 18-year interval between a dengue virus type 1 outbreak in 1977-1979 and a dengue virus type 2 outbreak in 1997 in santiago de cuba, cuba, provided a unique opportunity to evaluate risk factors for dengue disease. all patients with symptomatic dengue, including 205 cases of dengue hemorrhagic fever and 12 deaths, were adults born before the dengue virus type 1 epidemic, and nearly all (98%) experienced secondary dengue virus infections. in contrast, almost all of those who seroconverted witho ... | 2000 | 11085390 |