| seroepidemiology of human enterovirus71 and coxsackievirusa16 in jiangsu province, china. | the major etiology of hand, foot and mouth disease (hfmd) is infection with human enterovirus a (hev-a). among subtypes of hev-a, coxsackievirusa16 (coxa16) and enterovirus 71 (ev71) are major causes for recurrent hfmd among infants and children in jiangsu province, mainland china. here, we analyzed maternal antibodies between prenatal women and their neonates, to determine age-specific seroprevalence of human ev71 and coxa16 infections in infants and children aged 0 to 15 years. the results may ... | 2012 | 23102275 |
| two models for changes of ev71 immunity in infants and young children. | human enterovirus 71 (ev71) has been associated with outbreaks of hand-foot-and-mouth disease (hfmd) in china. susceptibility to ev71 is associated with age, but few studies have been accomplished to measure such a relationship. a better understanding of the connection between susceptibility and age is necessary to develop strategies for control of hfmd. in 2010, a survey of an epidemic of ev71 was conducted in a northern city of jiangsu province in china. samples were tested serologically to id ... | 2015 | 25906390 |
| enterovirus spectrum from the active surveillance of hand foot and mouth disease patients under the clinical trial of inactivated enterovirus a71 vaccine in jiangsu, china, 2012-2013. | epidemiological data from active surveillance on human enterovirus, which could cause hand, foot, and mouth disease, were limited. an active surveillance system was used to investigate the enterovirus spectrum and the incidence of different enteroviruses in infants aged 6-35 months in jiangsu province from 2012 to 2013. fifty-nine infants were randomly selected from 522 non-ev-a71/cv-a16 hfmd patients. we collected 173 throat swabs and 174 rectal swabs from these infants. rt-pcr was used to ampl ... | 2015 | 26010334 |