| the prevalence of neutralising antibodies to chimpanzee adenovirus type 6 and type 7 in healthy adult volunteers, patients with chronic hepatitis b and patients with primary hepatocellular carcinoma in china. | the presence of neutralising antibodies (nabs) against adenovirus in the population is a major hurdle preventing the effective use of replication-defective adenoviruses (ads) as candidates for gene therapy and vaccine vectors for many diseases. only a few studies have described the epidemiology of pre-existing immunity to chimpanzee ads in china. to assess the prevalence of nabs to chimpanzee adenovirus serotypes 6 and 7 (adc6 and adc7), we enrolled 998 healthy participants from five regions in ... | 2014 | 24057756 |