Publications

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studies on fastidious adenoviruses in ontario: a distinct strain associated with gastroenteritis.from 100 cases of gastroenteritis among children caused by adenovirus infection in ontario, 33 virus isolates were divided into three categories according to their biological behavior in tissue cultures. so far, the results of neutralization tests, structural protein analysis, and dna restriction patterns showed that the virus of category 1 was similar to adenovirus type 40. however, the adenovirus of category 2 was a distinct adenovirus which shared some similarities with adenovirus type 5. vir ...19863009537
adenoviral infection in captive moose (alces alces) in canada.adenoviral infection was associated with hemorrhagic enteritis, serosal hemorrhages, and severe pulmonary edema in six captive moose (alces alces) in toronto, ontario, canada: an adult female moose and three calves in 1985 and two calves in 1998. adenoviral disease was suspected based on histological findings of systemic vasculitis and widespread thrombosis associated with amphophilic intranuclear inclusions in endothelial cells. diagnosis was confirmed by immunohistochemistry using antiserum to ...200212216797
an assessment of onrab oral rabies vaccine persistence in free-ranging mammal populations in ontario, canada.onrab is a rabies glycoprotein recombinant human adenovirus type 5 oral vaccine developed for application in baits to control rabies in wildlife populations. prior to widespread use of onrab, both the safety and effectiveness of this vaccine required investigation. while previous research has focused on field performance and the persistence and pathogenicity of onrab in captive animals, we sought to examine persistence and shedding of onrab in populations of free-ranging target and non-target ma ...201323499602
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