| efficacy of dihydroartemisinin-piperaquine for treatment of uncomplicated plasmodium falciparum and plasmodium vivax in cambodia, 2008 to 2010. | we describe here the results of antimalarial therapeutic efficacy studies conducted in cambodia from 2008 to 2010. a total of 15 studies in four sentinel sites were conducted using dihydroartemisinin-piperaquine (dp) for the treatment of plasmodium falciparum infection and chloroquine (cq) and dp for the treatment of p. vivax infection. all studies were performed according to the standard world health organization protocol for the assessment of antimalarial treatment efficacy. among the studies ... | 2013 | 23208711 |
| higher microsatellite diversity in plasmodium vivax than in sympatric plasmodium falciparum populations in pursat, western cambodia. | previous microsatellite analyses of sympatric populations of plasmodium vivax and plasmodium falciparum in brazil revealed higher diversity in the former species. however, it remains unclear whether regional species-specific differences in prevalence and transmission levels might account for these findings. here, we examine sympatric populations of p. vivax (n=87) and p. falciparum (n=164) parasites from pursat province, western cambodia, where both species are similarly prevalent. using 10 geno ... | 2013 | 23562882 |
| chloroquine remains effective for treating plasmodium vivax malaria in pursat province, western cambodia. | chloroquine (cq) is used to treat plasmodium vivax malaria in areas where cq resistance has not been reported. the use of artemisinin (art)-based combination therapies (acts) to treat cq-sensitive p. vivax infections is effective and convenient but may promote the emergence and worsening of art resistance in sympatric plasmodium falciparum populations. here, we show that cq effectively treats p. vivax malaria in pursat province, western cambodia, where art-resistant p. falciparum is highly preva ... | 2014 | 25049249 |