| efficacy of dihydroartemisinin-piperaquine for treatment of uncomplicated plasmodium falciparum and plasmodium vivax in cambodia, 2008 to 2010. | we describe here the results of antimalarial therapeutic efficacy studies conducted in cambodia from 2008 to 2010. a total of 15 studies in four sentinel sites were conducted using dihydroartemisinin-piperaquine (dp) for the treatment of plasmodium falciparum infection and chloroquine (cq) and dp for the treatment of p. vivax infection. all studies were performed according to the standard world health organization protocol for the assessment of antimalarial treatment efficacy. among the studies ... | 2013 | 23208711 |
| reactive case-detection of malaria in pailin province, western cambodia: lessons from a year-long evaluation in a pre-elimination setting. | as momentum towards malaria elimination grows, strategies are being developed for scale-up in elimination settings. one prominent strategy, reactive case detection (racd), involves screening and treating individuals living in close proximity to passively detected, or "index" cases. this study aims to use racd to quantify plasmodium parasitaemia in households of index cases, and identify risk factors for infection; these data could inform reactive screening approaches and identify target risk gro ... | 2016 | 26931488 |
| history of malaria treatment as a predictor of subsequent subclinical parasitaemia: a cross-sectional survey and malaria case records from three villages in pailin, western cambodia. | treatment of the sub-clinical reservoir of malaria, which may maintain transmission, could be an important component of elimination strategies. the reliable detection of asymptomatic infections with low levels of parasitaemia requires high-volume quantitative polymerase chain reaction (upcr), which is impractical to conduct on a large scale. it is unknown to what extent sub-clinical parasitaemias originate from recent or older clinical episodes. this study explored the association between clinic ... | 2016 | 27118311 |