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primary amoebic meningoencephalitis in north queensland: the paediatric experience.primary amoebic meningoencephalitis (pam) is a fulminant, diffuse haemorrhagic meningoencephalitis caused by naegleria fowleri, with an almost invariably fatal outcome. in australia and the developed world, pam remains a rare disease, although it is very likely that large numbers of cases go undetected in developing countries. n. fowleri is a thermophilic, free-living amoeba with a worldwide distribution. it is acquired when contaminated fresh water is flushed into the nose and penetrates the ce ...201627681975
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