| clinical observations and virological study of aseptic meningitis in the kaohsiung area. | during 1988, an endemic outbreak of aseptic meningitis was noted in the kaohsiung area. throughout the year, a total of 89 cases were identified by cerebrospinal fluid (csf) examination at the pediatric department of kaohsiung medical college. the peak incidence was from june to october. scattered cases still occurred during november and december. the male to female ratio was 1.7:1 and the age distribution ranged from 1 month to 15 years old. two peaks of age distribution were observed; one in i ... | 1990 | 1981774 |
| outbreak of aseptic meningitis in taipei in spring 1993. | an outbreak of aseptic meningitis in the taipei area occurred from january to august 1993. a total of 114 cases were identified by cerebrospinal fluid (csf) examination at national taiwan university hospital. most of the cases were found from february to may 1993. the peak of age distribution was 3 to 11 years. the male-to-female ratio was 2.1 to 1. most patients had fever, headache, and vomiting and nausea. on initial csf examination, protein concentrations > 400 mg/l were noted in 38 of 93 csf ... | 1995 | 7613228 |
| the clinical evaluation of an outbreak of aseptic meningitis in children. | aseptic meningitis is a common disease in children; the present report describes the clinical and laboratory studies of 62 children involved in an outbreak of aseptic meningitis. | 1996 | 8634928 |
| laboratory diagnosis and genetic analysis of an echovirus 30-associated outbreak of aseptic meningitis in taiwan in 2001. | a large outbreak of aseptic meningitis occurred from april to november 2001 in taiwan. of the 1,130 enterovirus-infected patients, echovirus 30 (e30) infection was diagnosed in 188 (16.6%), with the patients having various clinical manifestations including aseptic meningitis (73.9%), young infant fever (6.9%), respiratory symptoms or herpangina (13.3%), or others (5.9%). the majority of the e30-infected patients were between 3 and 10 years old. of the 264 e30 strains identified, 94.3, 71, and 67 ... | 2002 | 12454133 |
| mosaic genome structure of echovirus type 30 that circulated in taiwan in 2001. | an echovirus type 30 (e30) outbreak occurred in taiwan in 2001. in this study, one 1998 and nineteen 2001 enterovirus isolates from cerebrospinal fluid (csf) of children with meningitis were genetically analyzed. although negative results were obtained using the e30-specific monoclocal antibody in an immunofluorescent assay (ifa) test of all 20 isolates, molecular typing by partial vp1 sequences and subsequent neutralization test identified them as e30. among those, seven of them were misidentif ... | 2007 | 17610124 |
| molecular epidemiology of echovirus 30 in taiwan, 1988-2008. | to investigate the molecular epidemiology of taiwanese echovirus 30 (e-30) strains, we analyzed the 876 bp sequence of the vp1 gene from 32 taiwanese strains isolated in 1988-2008, 498 reference sequences, and one echovirus 21 strain as the out-group. phylogenetic analysis detected six e-30 genotypes (designated gi-gvi) that had circulated globally during the past five decades. the genotypes varied widely in geographic distribution and circulation half-life. the gi, gii, and gv were ancient geno ... | 2011 | 21369829 |
| epidemiologic and clinical features of non-polio enteroviral infections in northern taiwan in 2008. | background: non-polio enteroviruses may cause different diseases, including herpangina, hand-foot-mouth disease (hfmd), meningitis, and nonspecific febrile illness; and cause epidemic outbreak annually. this study delineates the diversity of clinical presentations based on different serotypes and different groups [human enterovirus (hev)-a and hev-b] of enteroviruses (evs) during the 2008 epidemic in national taiwan university hospital (ntuh). methods: we retrospectively identified patients youn ... | 2011 | 21524954 |