Publications
inhibitory effects of wild bitter melon leaf extract on propionibacterium acnes-induced skin inflammation in mice and cytokine production in vitro. | propionibacterium acnes is a key pathogen involved in acne inflammation. wild bitter melon (wbm, momordica charantia l. var. abbreviate seringe) is consumed as both a vegetable and as folk medicine in taiwan. we examined the inhibitory activity of the total phenolic extract (tpe) of wbm leaf on p. acnes-induced inflammatory responses in vivo and in vitro. our data showed that tpe significantly attenuated p. acnes-induced ear swelling in mice along with microabscess. flow cytometry analysis revea ... | 2015 | 26098998 |
anaerobic bacterial meningitis in adults. | anaerobic infection is a very uncommon condition in adult bacterial meningitis (abm), and its clinical characteristics have yet to be clarified. we enrolled 540 patients with culture-proven bacterial meningitis during a study period of 30 years (1986-2015), of whom 13 (2.4%) had anaerobic infections. these 13 patients were eight men and five women, aged 22-77 years. among them, 53.8% (7/13) had a postneurosurgical state as the preceding event, and 79.6% (10/13) had underlying medical conditions ... | 2018 | 29396061 |