| viral load in blood is correlated with disease severity of neonatal coxsackievirus b3 infection: early diagnosis and predicting disease severity is possible in severe neonatal enterovirus infection. | we conducted a study during an outbreak of coxsackievirus b3 infection in 2005 and found that viral rna could be detected in patients' blood specimens soon after the onset of fever, and the level of viral rna was positively correlated with disease severity. timely diagnosis is possible in severe neonatal enterovirus infection. | 2007 | 17443457 |
| molecular epidemiology of coxsackievirus b3. | molecular epidemiological characteristics are needed to understand the impact of coxsackievirus b3 (cv-b3) infection, since no cv-b3 genotyping literature is available. twenty-nine cv-b3 taiwan strains obtained from 1992 to 2005 were analyzed. a phylogenetic tree was constructed based on the 290 nucleotide sequence of the vp1 gene of taiwan isolates and in 91 other cv-b3 genbank sequences. five genotypes (gi-gv) were depicted. the gi, gii, and giii were dominant in america and europe, whereas gi ... | 2010 | 20398802 |
| epidemic pleurodynia caused by coxsackievirus b3 at a medical center in northern taiwan. | epidemic pleurodynia is seldom reported in southeast asia and there has been no report from taiwan. we conducted a retrospective chart review of children = 18 years of age in the national taiwan university hospital from january 1 to december 31, 2005. epidemic pleurodynia was defined as an acute illness characterized by sharp localized pain over the chest or upper abdomen. patients with known heart diseases or pulmonary consolidations were excluded. in total, 28 patients met the case definition ... | 2010 | 21195979 |
| high incidence of mammalian orthoreovirus identified by environmental surveillance in taiwan. | wild poliovirus (wpv) persists in diverse locales worldwide, spreading outward from endemic areas. in response to the international threat of wpv transmission and changes in the national vaccination policy, we established an environmental surveillance system to monitor the circulation of wild and vaccine-related poliovirus in taiwan. from july 2012 to december 2013, we collected sewage specimens every month from 10 sewage treatment plants located throughout taiwan. the specimens were concentrate ... | 2015 | 26555962 |
| phylogenetic analysis and development of an immunofluorescence assay for untypeable strains of coxsackievirus b3. | in recent years, coxsackievirus b3 (cv-b3) has been determined as a dominant enterovirus serotype that may cause severe complications in patients. since 2008 in taiwan, some enterovirus isolates have been regarded as untypeable [by employing commercial immunofluorescence assay (ifa) kits]. in 2012, the number of isolates increased. genetic sequence analysis further confirmed that cv-b3 was present in most of the untypeable viruses. | 2014 | 23993765 |
| hepatic damage caused by coxsackievirus b3 is dependent on age-related tissue tropisms associated with the coxsackievirus-adenovirus receptor. | coxsackievirus b (cvb) and enterovirus 71 (ev71) are important causes of severe enteroviral diseases in neonates or young children in taiwan. cvb can cause fulminant hepatitis, myocarditis or meningoencephalitis. this study was designed to explore the role of coxsackievirus-adenovirus receptor (car) in the pathogenesis of cvb3-infected hepatocytes via in vitro and mice studies. cvb3 (cvb3/2630) was isolated from liver tissue of a neonate with fulminant hepatitis. cell lines a549, hela, hep2 and ... | 2013 | 23620416 |