Publications
| diagnostic sensitivity of polymerase chain reaction and southern blot hybridization for the detection of human papillomavirus dna in biopsy specimens from cervical lesions. | human papillomaviruses (hpvs) are associated with benign and malignant neoplasms of the cervix. one of the criteria for their etiologic role requires an assessment of whether virtually all or only a small fraction of lesions contain viral genomes. dna preparations from colposcopically directed punch biopsies of cervical lesions were analyzed by southern blot hybridization and the polymerase chain reaction (pcr) for the presence of hpv dna. the biopsy specimens represented different pathologic en ... | 1991 | 1850950 |
| human papillomavirus in dysplasia and carcinoma of the cervix in singapore. | a prospective study was conducted in singapore in 1985 where 107 women with abnormal cervical smears were studied for cervical neoplasia and its association with the human papillomaviruses (hpv), using hpv 11, 16 and 18 dna as probes. cervical biopsies were performed for histology as well as for dna southern blot hybridization studies to detect the presence of hpv 11, 16 or 18 genome. the prevalence of the various types of papillomavirus dna in cervical tissue samples from cervical carcinoma and ... | 1988 | 2853859 |