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adaptation of genetically monomorphic bacteria: evolution of copper resistance through multiple horizontal gene transfers of complex and versatile mobile genetic elements.copper-based antimicrobial compounds are widely used to control plant bacterial pathogens. pathogens have adapted in response to this selective pressure. xanthomonas citri pv. citri, a major citrus pathogen causing asiatic citrus canker, was first reported to carry plasmid-encoded copper resistance in argentina. this phenotype was conferred by the coplab gene system. the emergence of resistant strains has since been reported in réunion and martinique. using microsatellite-based genotyping and co ...201728101896
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