Publications

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dengue seroprevalence in the french west indies: a prospective study in adult blood donors.using an anti-dengue immunoglobulin g (igg) indirect enzyme-linked immunosorbent assay, seroprevalence was determined among 783 adult blood donors in the french caribbean islands of guadeloupe and martinique in 2011. overall, 93.5% [91.5; 95.1] samples were positive for dengue antibodies, 90.7% (350 of 386) in martinique and 96.2% (382 of 397) in guadeloupe. only 30% of these adults recalled having had dengue disease before. serotype-specific neutralization assays applied to a subset of igg-posi ...201525846291
[the prevention of dengue in guadeloupe].dengue is the only disease transmitted by mosquitoes in the guadeloupe islands of french antilles. two dengue outbreaks were reported in 1992 and 1994. aedes aegypti is recognized the only vector of dengue in guadeloupe, and the 200 l drums are the most important breeding-sites. vector control in guadeloupe includes community health education, larvicide and adulticide spraying, and the destruction of the breeding-sites. however, ae. aegypti control has limitations such as the lack of participati ...19968924773
time series analysis of dengue incidence in guadeloupe, french west indies: forecasting models using climate variables as predictors.during the last decades, dengue viruses have spread throughout the americas region, with an increase in the number of severe forms of dengue. the surveillance system in guadeloupe (french west indies) is currently operational for the detection of early outbreaks of dengue. the goal of the study was to improve this surveillance system by assessing a modelling tool to predict the occurrence of dengue epidemics few months ahead and thus to help an efficient dengue control.201121658238
[mother-infant dengue transmission during the 2009-2010 dengue epidemic: report of four cases].the risks related to dengue virus infection during pregnancy have been increasingly better described over the past 10 years. the possibility of maternal-fetal transmission is now recognized, but the diagnosis is still too late because of a wide range of clinical signs that the infected newborn child can present. from december 2009 to october 2010, guadeloupe island underwent an exceptional dengue epidemic. during this epidemic, at least four cases of vertical virus transmission were biologically ...201424938916
deep thrombocytopenia due to dengue fever in a patient splenectomized for immune thrombocytopenia. 201222365342
parity and longevity of aedes aegypti according to temperatures in controlled conditions and consequences on dengue transmission risks.in guadeloupe, aedes aegypti mosquitoes are the only vectors of dengue and chikungunya viruses. for both diseases, vector control is the only tool for preventing epidemics since no vaccine or specific treatment is available. however, to efficiently implement control of mosquitoes vectors, a reliable estimation of the transmission risks is necessary. to become infective an ae. aegypti female must ingest the virus during a blood meal and will not be able to transmit the virus during another blood- ...201526258684
lessons raised by the major 2010 dengue epidemics in the french west indies.dengue fever has been endemo-epidemic in the whole region of america. in 2010, guadeloupe and martinique experienced historical epidemics, with an estimated attack rate of 10% in two islands. when considering the temporal evolution of epidemiological indicators, an unusual increase in the number of dengue cases could be detected very early. two main factors might have facilitated the settlement of a viral transmission despite the dry season: a low immunity of the population against the circulati ...201424315801
[dengue outbreaks in the french west-indies in a context of arbovirosis emergence and reemergence].in the french west indies (martinique, guadeloupe and french guyana), dengue represents a model of a reemerging arbovirosis, with hyperendemicity and more severe cases and deaths than previously observed co-circulation of the four serotypes, the increasing number of cases during interepidemic periods, and the increase in severe forms (particularly hemorrhagic forms), are signs of forthcoming hyperendemicity. den-2 is the viral subtype most frequently associated with severe forms. other arboviros ...200819024949
[acute renal failure after dengue virus infection: a pediatric case report].dengue is an emerging, rapidly expanding disease, whose clinical and biological manifestations vary. kidney injury is not usual but can be severe, and it is most often associated with dengue hemorrhagic fever or shock. guadeloupe, which is located in an endemic area, experienced an epidemic from 2013 to 2014. during this outbreak, a case of renal failure during dengue was observed in a 10-year-old child. no evidence of dengue hemorrhagic fever or shock syndrome was found. the clinical and biolog ...201626563725
[rheumatoid purpura discovered during dengue fever]. 19989887467
[dengue fever with neurologic expression. three cases in adults].dengue fever, unlike most other arboviral diseases, does not usually cause encephalitis. however, neurologic symptoms with poor prognosis have been regularly reported, mostly in asian children affected by the severe dengue hemorrhagic fever/dengue shock syndrome, and attributed to a non specific, anoxic or metabolic encephalopathy. recently, first isolations of dengue viruses from csf or brain tissue, have renewed this concept. we report 3 dengue fever cases with neurologic manifestations and fa ...199910392255
dengue surveillance in the french armed forces: a dengue sentinel surveillance system in countries without efficient local epidemiological surveillance.surveillance of travel-acquired dengue could improve dengue risk estimation in countries without ability. surveillance in the french army in 2010 to 2011 highlighted 330 dengue cases, mainly in french west indies and guiana: denv-1 circulated in guadeloupe, martinique, french guiana, new caledonia, djibouti; denv-3 in mayotte and djibouti; and denv-4 in french guiana.201223809078
[epidemic of influenza a(h1n1) 2009 in the french overseas territories of the americas: epidemiological surveillance set up and main results, april 2009-january 2010.]guadeloupe, french guiana, martinique, st. martin and st. barthelemy were the french territories most exposed to the new influenza a(h1n1)v, and adequate epidemiological surveillance tools were promptly developed in order to detect its emergence. the first stage, "containment phase", consisted in detection and management of individual cases. then, when an autochthonous a(h1n1)v circulation was confirmed, its evolution has been monitored within the whole population, mainly through data collected ...201021181330
[emergence of dengue hemorrhagic fever in french antilles. 3 initial fatal cases in guadeloupe].two outbreaks of dengue hemorrhagic fever occurred in guadeloupe (french west indies) in successive epidemics in 1994 and 1995. the first outbreak was caused by den-2 virus and the second by den-1.19989793052
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