experimental cerebral ischemia: the contribution of the bethesda group. | igor klatzo started his research on cerebral ischemia at the nih in the 1960s. the mechanism that produces the blood-brain barrier change after ischemia was a focus of interest in klatzo's experiments, which used larger mammals. studies using mongolian gerbils, started by u. ito, resulted in several important findings, including observation of the maturation phenomenon in 1975. using newly developed ischemia models, the mechanism of postischemic neuronal/tissue injury was extensively studied. th ... | 2010 | 19812914 |