| glutathione s-transferase expression in pollution-associated hepatic lesions of brown bullheads (ameiurus nebulosus) from the cuyahoga river, cleveland, ohio. | in rodents, overexpression of glutathione s-transferase pi is a characteristic feature of foci of cellular alteration (fca) and neoplastic liver lesions induced by genotoxic chemicals. alterations of glutathione s-transferase (gst) expression in hepatic lesions have also been reported in fish exposed to environmental carcinogens, and cellular gst expression may be an important determinant of growth and progression of chemical-associated liver tumors in certain fish species. in the present study, ... | 2004 | 15071171 |
| decline in liver neoplasms in wild brown bullhead catfish after coking plant closes and environmental pahs plummet. | polycyclic aromatic hydrocarbons (pahs) in both sediment and brown bullhead catfish tissues from the black river in lorain county, ohio, declined by 65% and 93%, respectively, between 1980 and 1982. sediment pahs declined an additional 99% by 1987, coincident with the closure of a coking facility in 1983. contemporaneously, liver cancer in 3- to 4-year-old brown bullheads declined to about one-quarter the 1982 frequency (10% versus 39%) by 1987, while the percentage of livers without any prolife ... | 1995 | 7737065 |
| pathological and serum chemistry profiles of brown bullheads (ameiurus nebulosus) from the black river and old woman creek, ohio. | | 1995 | 7756785 |