| genetic and dietary predictors of cyp2e1 activity: a phenotyping study in hawaii japanese using chlorzoxazone. | cytochrome p4502e1 (cyp2e1) is considered to play an important role in the metabolic activation of procarcinogens such as n-nitrosoamines and low molecular weight organic compounds. an rsai polymorphism is present in the 5'-flanking region of the cyp2e1 gene, which could possibly affect its transcription. however, the relationship between genotype and the phenotypic catalytic activity of the enzyme has not been defined. also, the effects in humans of specific dietary factors, other than ethanol, ... | 1999 | 10385138 |