Publications

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unusual physiology of scale-less carp, gymnocypris przewalskii, in lake qinghai: a high altitude alkaline saline lake.the scale-less carp (gymnocypris przewalskii) inhabits lake qinghai located on the qinghai-tibet plateau (elevation, 3200 m) in western china. the lake waters are alkaline (ph 9.4, titratable alkalinity=30 mmol l(-1)), mg(2+)-rich (18.7 mmol l(-1)), ca(2+)-poor (0.30 mmol l(-1)) and saline (9 per thousand ). these fish make annual spawning migrations into freshwater rivers. we investigated the physiology of nitrogen excretion and ionoregulation of fish from the lake and river. fish from both wat ...200312547271
evolution and regulation of the downstream gene of hypoxia-inducible factor-1alpha in naked carp (gymnocypris przewalskii) from lake qinghai, china.the naked carp (gymnocypris przewalskii) is a native teleost of lake qinghai (altitude, 3.2 km) on the qinghai-tibet plateau in china. hypoxia-inducible factor (hif)-1alpha of gymnocypris przewalskii was cloned and a phylogenetic tree for vertebrate hif-1alpha was constructed. by analysis of maximum likelihood models of codon substitutions for hif-1alpha, three positive sites in the branch lineages of crucian carp, eelpout, and flounder, and a higher proportion of neutral sites in naked carp, an ...200818941827
growth hormone and insulin-like growth factor of naked carp (gymnocypris przewalskii) in lake qinghai: expression in different water environments.here, we report the cloning and characterization of growth hormone (gh), insulin-like growth factor-i (igf-i) and igf-ii from naked carp (gymnocypris przewalskii), a native teleost fish of lake qinghai in the qinghai-tibet plateau of china. the gh of naked carp encodes for a predicted amino acid sequence showing identities of 63%, 63%, 91% and 94% with cherry salmon, rainbow trout, zebrafish and grass carp, respectively. compared to common carp and goldfish, evolutionary analysis showed that gen ...200919233187
positive darwinian selection within interferon regulatory factor genes of gymnocypris przewalskii (cyprinidae) on the tibetan plateau.tibetan plateau (tp) had experienced phased uplift, resulting in inhospitable environment of low temperature, hypoxia and high ultraviolet radiation for tibetan wildlife. many organisms can well adapt to tp, it is of ecological and evolutionary interest to untangle how organisms adapt to extreme environment on tp through evolution. previous studies mainly focused on hypoxia and metabolism related genes, but we know little about the evolutionary history of immune genes in tibetan wildlife. in thi ...201626774494
cloning and characterization of two subunits of calcineurin cdna in naked carp (gymnocypris przewalskii) from lake qinghai, china.the naked carp (gymnocypris przewalskii), a native teleost, plays an important role in maintenance of the ecological balance in the system of lake qinghai (altitude, 3.2 km) on the qinghai-tibet plateau in china. calcineurin (cn) is the only member of the serine/threonine phosphatase family that can be activated by both ca2+ and calmodulin (cam) and involved in many important physiological processes such as salt tolerance/adaption. in this report, cdnas of cn catalytic subunit paralogue isoforms ...201425308739
heavy metals levels in fish from aquaculture farms and risk assessment in lhasa, tibetan autonomous region of china.fish is consumed as a common food by humans due to its nutritional and therapeutic benefits. however, they can accumulate toxic chemicals (such as heavy metals, persistent organic pollutants) from water and food chain. very few studies have been investigated on heavy metal contents in fish from tibetan autonomous region of china. in order to study heavy metals levels in fish from aquaculture farms and evaluate the risk that human consume fish in this area, we collected four types of aquaculture ...201424671559
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