| a cys374tyr homozygous mutation of platelet glycoprotein iiia (beta 3) in a chinese patient with glanzmann's thrombasthenia. | a 20-year-old woman from a consanguineous family in the hunan province of the people's republic of china was diagnosed as having glanzmann's thrombasthenia based on (1) nearly a lifelong history of epistaxis, gum bleeding, petechiae, and purpura; (2) severe menorrhagia resulting in anemia and need for whole-blood transfusion; (3) normal coagulation assays; (4) prolonged bleeding time; (5) absent clot retraction; (6) decreased glass bead retention; (7) absent platelet aggregation in response to a ... | 1996 | 8781422 |