| transcriptional analysis of four family 4 p450s in a puerto rico strain of aedes aegypti (diptera: culicidae) compared with an orlando strain and their possible functional roles in permethrin resistance. | a field strain of aedes aegypti (l.) was collected from puerto rico in october 2008. based on ld50 values by topical application, the puerto rico strain was 73-fold resistant to permethrin compared with a susceptible orlando strain. in the presence of piperonyl butoxide, the resistance of puerto rico strain of ae. aegypti was reduced to 15-fold, suggesting that cytochrome p450-mediated detoxification is involved in the resistance of the puerto rico strain to permethrin. to determine the cytochro ... | 2014 | 24897853 |