Publications

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association of hla class i with severe acute respiratory syndrome coronavirus infection.the human leukocyte antigen (hla) system is widely used as a strategy in the search for the etiology of infectious diseases and autoimmune disorders. during the taiwan epidemic of severe acute respiratory syndrome (sars), many health care workers were infected. in an effort to establish a screening program for high risk personal, the distribution of hla class i and ii alleles in case and control groups was examined for the presence of an association to a genetic susceptibly or resistance to sars ...200312969506
a pbtk/td modeling-based approach can assess arsenic bioaccumulation in farmed tilapia (oreochromis mossambicus) and human health risks.a biologically based risk-assessment model of arsenic (as) exposure evaluated farmed tilapia (orechromis mossambicus) and human health during tilapia consumption in an area of southwestern taiwan where blackfoot disease (bfd) occurs. the risk assessment addressed exposures to city residents who lived in taipei, taichung, and kaohsiung, as well as subsistence fishers living in the bfd area who consumed tilapia. the models implemented included a physiologically based toxicokinetic and toxicodynami ...200516637146
the association of single nucleotide polymorphisms in the 5'-regulatory region of the lumican gene with susceptibility to high myopia in taiwan.to study the relationships between single nucleotide polymorphisms (snps) of lumican, decorin, and dspg3 genes and high myopia.200616902402
prognostic impact of p16, p53, epidermal growth factor receptor, and human papillomavirus in oropharyngeal cancer in a betel nut-chewing area.to evaluate the prevalence of human papillomavirus (hpv) and the prognostic significance of epidermal growth factor receptor (egfr), p53, and p16 among patients with oropharyngeal carcinoma.201020479383
conservation of the eastern taiwan strait chinese white dolphin (sousa chinensis): fishers' perspectives and management implications.the abundance of the eastern taiwan strait (ets) population of the chinese white dolphin (sousa chinensis) has been estimated to be less than 100 individuals. it is categorized as critically endangered in the iucn red list of threatened species. thus, immediate measures of conservation should be taken to protect it from extinction. currently, the taiwanese government plans to designate its habitat as a major wildlife habitat (mwh), a type of marine protected area (mpa) for conservation of wildli ...201627526102
mixture risk assessment due to ingestion of arsenic, copper, and zinc from milkfish farmed in contaminated coastal areas.human health risks associated with the consumption of metal-contaminated fish over extended periods have become a concern particularly in taiwan, where fish is consumed on a large scale. this study applied the interaction-based hazard index (hi) to assess the mixture health risks for fishers and non-fishers who consume the arsenic (as), copper (cu), and zinc (zn) contaminated milkfish from as-contaminated coastal areas in taiwan, taking into account joint toxic actions and potential toxic intera ...201728452032
comparison study of clinical outcomes between single-site robotic cholecystectomy and single incision laparoscopic cholecystectomy.multiport laparoscopic cholecystectomy is the standard surgical procedure for symptomatic gallbladder diseases. the latest evolution is single incision laparoscopic cholecystectomy (silc). single-site robotic cholecystectomy (ssrc) overcomes several limitations of manual silc. the aim of this study is to present our initial experiences in ssrc and to compare its clinical outcomes with those of silc.201627188234
the protective effect of helmet use in motorcycle and bicycle accidents: a propensity score-matched study based on a trauma registry system.transportation by motorcycle and bicycle has become popular in taiwan, this study was designed to investigate the protective effect of helmet use during motorcycle and bicycle accidents by using a propensity score-matched study based on trauma registry system data.201728784110
influenza-associated central nervous system dysfunction in taiwanese children: clinical characteristics and outcomes with and without administration of oseltamivir.seventy-four of the 2651 patients (2.8%) with influenza aged <18 years had signs or symptoms of central nervous system dysfunction presenting to the hospital. none had oseltamivir exposure before the onset of central nervous system dysfunction. seventeen children received oseltamivir therapy after admission and no significant difference between administration of oseltamivir and outcome was observed (p = 0.1512 by fisher exact test).200919483663
toxicokinetics/toxicodynamics of arsenic for farmed juvenile milkfish chanos chanos and human consumption risk in bfd-endemic area of taiwan.this paper presents a toxicokinetic/toxicodynamic analysis to appraise arsenic (as) bioaccumulation in farmed juvenile milkfish chanos chanos at blackfoot disease (bfd)-endemic area in taiwan, whereas probabilistic incremental lifetime cancer risk (ilcr) and hazard quotient (hq) models are also employed to assess the range of exposures for the fishers and non-fishers who eat the contaminated fish. we conducted a 7-day exposure experiment to obtain toxicokinetic parameters, whereas a simple criti ...200616513169
guillain-barré syndrome in southern taiwan: clinical features, prognostic factors and therapeutic outcomes.to determine the clinical features, prognostic factors, and therapeutic results of guillain-barré syndrome (gbs) in order to improve the therapeutic strategy for this disease. we retrospectively reviewed the electrodiagnostic study and medical records of patients with gbs admitted to chang gung memorial hospital, kaohsiung, between january 1986 and december 2000. outcomes and prognosis were followed-up after 1 year. ninety-six patients were enrolled in this study. according to the clinical and e ...200314641510
cross-cultural assessment of process skills.a standardized activities of daily living evaluation that has acceptable psychometric qualities, can relate discrete component skills to functional performance, includes culture-relevant test items, is standardized on culture-specific samples, and is free of cultural bias is needed to evaluate diverse cultural populations. the assessment of motor and process skills (amps) (fisher, 1990a) offers a unique solution. the amps consists of 35 motor and process skill items assumed to represent two univ ...19921463059
does trauma etiology affect the pattern of mandibular fracture?the purpose of the present study was to evaluate the relationship between trauma etiologies and anatomic sites of mandibular fractures.201222976719
focused life history data and linear enamel hypoplasia to help explain intergenerational variation in relative leg length within taiwanese families.this study first examines the hypothesis that significant intergeneration increases in stature within 85 taiwanese families in two study locations were primarily the result of increases in subischial leg length. it then evaluates a second hypothesis that independent assessments of the extent of intergenerational change in childhood environments within these families helped account for parent-offspring differences in relative leg length. childhood environments were assessed using two criteria: de ...200717421011
different profiles of allergen sensitization in different ages and geographic areas in changhua, taiwan.environmental factors, different ages, and detection methods might affect the profiles of allergy sensitization and confound the diagnosis of allergic diseases. the purpose of this study was to investigate the different profiles of allergen sensitization in different ages, geographic areas, and detection methods.201323058910
[retrospective review and analysis of the results of taiwan nurses association nursing projects from 2004 to 2005].although a nursing project is one of the important n4 professional competence training courses in the clinical ladder system, little research on its effectiveness can be found. this study therefore aimed to analyze the demographics, hospital characteristics, scores, and pass rates for the taiwan nurses association's 2004 to 2005 nursing projects and to compare the differences between them. the design was retrospective content analysis and the data sources were nursing project reviewer sheets fro ...200717431840
mortality rates under the care of junior and senior surgery residents in a surgical intensive care unit/neurologic intensive care unit: a 5-year retrospective cohort study at taoyuan armed forces general hospital.the quality and outcome of health care administered in intensive care units (icus) of teaching hospitals are dependent on a myriad of factors; however, few studies have assessed mortality rates and length of stay in surgical intensive care and neurologic intensive care units (sicu/nicu) in relation to the experience of junior and senior surgery residents.200819056021
guillain-barré syndrome in taiwan: a clinical study of 167 patients.to identify clinical characteristics of various forms of guillain-barré syndrome in taiwan.19979343130
the risk factors, costs, and survival analysis of invasive vre infections at a medical center in eastern taiwan.to analyze 48 cases the risk factors of vancomycin-resistant enterococcus (vre) infections, the antibiotic costs after infection, and the survival conditions.201727836794
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