| erinacine s, a rare sesterterpene from the mycelia of hericium erinaceus. | a new sesterterpene, erinacine s, and one cyathane diterpene xyloside, erinacine a, were isolated from the ethanol extract of the mycelia of hericium erinaceus. their structures were elucidated by spectroscopic and x-ray analysis. a 30-day oral course of erinacines a and s attenuated aβ plaque burden in the brains of 5-month-old female app/ps1 transgenic mice. moreover, erinacines a and s significantly increased the level of insulin-degrading enzyme in cerebral cortex. | 2016 | 26807743 |