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amelioration of oxidative stress in red blood cells from patients with beta-thalassemia major and intermedia and e-beta-thalassemia following administration of a fermented papaya preparation.in beta-hemoglobinopathies, such as beta-thalassemia (thal) and sickle cell anemia, the primary defects are mutations in the beta-globin gene. however, many aspects of the pathophysiology are mediated by oxidative stress. fermented papaya preparation (fpp), a natural health food product obtained by biofermentation of carica papaya, has been shown to limit oxidative stress both in vitro and in vivo. we studied the effect of fpp on two groups of beta-thal patients: beta-thal, major and intermedia, ...201020127662
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