| evaluation of pyridoacridine alkaloids in a zebrafish phenotypic assay. | three new minor components, the pyridoacridine alkaloids 1-hydroxy-deoxyamphimedine (1), 3-hydroxy-deoxyamphimedine (2), debromopetrosamine (3), and three known compounds, amphimedine (4), neoamphimedine (5) and deoxyamphimedine (6), have been isolated from the sponge xestospongia cf. carbonaria, collected in palau. structures were assigned on the basis of extensive 1d and 2d nmr studies as well as analysis by hresims. compounds 1-6 were evaluated in a zebrafish phenotype-based assay. amphimedin ... | 2010 | 20631869 |