application of monoclonal antibodies in functional and comparative investigations of heavy-chain immunoglobulins in new world camelids. | of the three immunoglobulin g (igg) isotypes described to occur in camelids, igg2 and igg3 are distinct in that they do not incorporate light chains. these heavy-chain antibodies (hcabs) constitute approximately 50% of the igg in llama serum and as much as 75% of the igg in camel serum. we have produced isotype-specific mouse monoclonal antibodies (mabs) in order to investigate the roles of hcabs in camelid immunity. seventeen stable hybridomas were cloned, and three mabs that were specific for ... | 2005 | 15753251 |