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induction of liver tumors by aflatoxin b1 in the tree shrew (tupaia glis), a nonhuman primate.the epidemiological studies suggest that aflatoxins, the toxic metabolites of the ubiquitous mold aspergillus flavus, may play a significant role in the evolution of hepatocellular carcinoma in man in certain geographic areas of the world. to ascertain their carcinogenicity in nonhuman primates, we have administered highly purified aflatoxin b1, intermittently in the diet at 2 ppm, to 10 female and 8 male tree shrews. the tree shrew (tupaia glis) is a nonhuman primate occurring throughout southe ...1976174805
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