experimental mycobacterium tuberculosis infection in the chinese tree shrew. | in recent years, the chinese tree shrew has been considered to be a promising experimental animal for numerous diseases. yet the susceptibility of mycobacterium tuberculosis (mtb) in chinese tree shrew is still unknown. we infected chinese tree shrews with a high dose (2.5 × 10(6) cfu) or a low dose (2.5 × 10(3) cfu) of the h37rv strain via the femoral vein to cause severe or mild disease. disease severity was determined by clinical signs, pathologic changes and bacteria distribution in organs. ... | 2014 | 25296288 |