| structures of haemoglobin from woolly mammoth in liganded and unliganded states. | the haemoglobin (hb) of the extinct woolly mammoth has been recreated using recombinant genes expressed in escherichia coli. the globin gene sequences were previously determined using dna recovered from frozen cadavers. although highly similar to the hb of existing elephants, the woolly mammoth protein shows rather different responses to chloride ions and temperature. in particular, the heat of oxygenation is found to be much lower in mammoth hb, which appears to be an adaptation to the harsh hi ... | 2012 | 23090393 |