| nasopharyngeal cryptococcosis. | naturally occurring cryptococcosis in five cats, a dog and a koala is described. involvement of the nasopharynx was documented in all patients, and nasopharyngeal mass lesions accounted for the major presenting complaints in four. signs referable to nasopharyngeal disease included snoring, stertor, inspiratory dyspnoea and aerophagia. diagnoses were made by caudal rhinoscopy using a retroverted flexible endoscope, vigorous orthograde flushing with saline, or at necropsy. concurrent cryptococcal ... | 1997 | 9258419 |
| serum antibody response to cryptococcus neoformans in cats, dogs and koalas with and without active infection. | anti-cryptococcal antibodies were measured in normal cats, dogs, horses and koalas, and cats, dogs and koalas with cryptococcosis using an enzyme immunoassay. antibody levels were expressed as absorbance readings. over 80% of cats and dogs with cryptococcal infection had elevated antibody levels at the time of diagnosis, during or after successful therapy. antibody levels in these patients either remained elevated or declined slowly after treatment. for cats, anti-cryptococcal antibody levels we ... | 1999 | 10200933 |
| asymptomatic carriage of cryptococcus neoformans in the nasal cavity of the koala (phascolarctos cinereus). | over a 22-month period, sequential nasal and skin swabs were obtained from 52 healthy captive koalas (phascolarctos cinereus) from the sydney region. cryptococcus neoformans was isolated in 17 koalas from 64 of 262 (24%) nasal swabs and from nine of 262 (3%) skin swabs. prevalence of nasal colonization varied seasonally from 12% (3/25) to 38% (10/26). cryptococcus neoformans var. gattii alone was cultured from 37, var. neoformans alone from 22 and both varieties from five nasal swabs. of 33 koal ... | 1999 | 10520157 |
| a queensland koala kept in a japanese zoological park was carrier of an imported fungal pathogen, filobasidiella neoformans var. bacillispora (cryptococcus neoformans var. gattii). | | 2002 | 11971161 |
| cryptococcus neoformans in the koala (phascolarctos cinereus): colonization by c n. var. gattii and investigation of environmental sources. | this study is the one in a series looking at the relationship among cryptococcus neoformans var. gattii, koalas and the environment. the koala was used as a natural biological sampler in an attempt to understand the dynamics of c. neoformans var. gattii in australian environments. evidence of asymptomatic nasal and skin colonization for extended periods by large numbers of c. n. var. gattii was obtained and geographical factors assessed. the key finding was the ability of koalas to amplify numbe ... | 2002 | 12146756 |
| cryptococcus neoformans var. gattii in the koala (phascolarctos cinereus): serological evidence for subclinical cryptococcosis. | cryptococcus neoformans var. gattii has been shown to have a strong association with eucalypts frequently used by koalas and, not surprisingly, it has been shown to colonize the nasal cavities of koalas. the progression from nasal colonization to tissue invasion is critical to understanding the pathogenesis of cryptococcosis in this species and provides a model for pathogenesis of cryptococcosis in other species. cryptococcal antigenaemia was detected in twenty-eight healthy koalas from three di ... | 2002 | 12146757 |
| cryptococcus neoformans var. gattii in the koala (phascolarctos cinereus): a review of 43 cases of cryptococcosis. | details of 11 previously reported cases and 32 new cases of cryptococcosis in captive and wild koalas were analysed. cryptococcus neoformans var. gattii accounted for all 29 cases in which varietal status was determined. no age or sex predisposition was observed. the respiratory tract was the primary focus of disease in 77% of cases. although the lower respiratory tract was affected most commonly (60% of cases), 30% of cases had upper respiratory tract lesions and 14% had both. dissemination was ... | 2003 | 12964714 |
| detection and identification of probable endemic fungal pathogen, cryptococcus gattii, and worldwide pathogen, cryptococcus neoformans, by real-time pcr. | a real-time pcr method for detection and identification of cryptococcus neoformans and cryptococcus gattii was developed and evaluated using dna from single-colony or koala nasal smears. two taqman minor groove binder probes that distinguished between these species were designed corresponding to the internal sequences of the cap59 gene for both species. the real-time pcr assay had 100% specificity, as assessed using 13 reference strains and 300 environmental strains. twelve smear samples from he ... | 2011 | 21623899 |
| long-term surveillance and treatment of subclinical cryptococcosis and nasal colonization by cryptococcus neoformans and c. gattii species complex in captive koalas (phascolarctes cinereus). | cryptococcosis is an important systemic mycosis caused by members of the cryptococcus neoformans species complex. this disease is potentially fatal in various animals, including koalas. we describe the long-term surveillance and treatment of subclinical cryptococcosis and nasal colonization of koalas by cryptococcus neoformans and c. gattii. of the 15 animals investigated through the use of samples obtained by nasal swabs, antigen titer measurements, and pathologic examination, c. neoformans was ... | 2011 | 21859391 |
| atypical presentation of cryptococcus neoformans in a koala (phascolarctos cinereus): a magnetic resonance imaging and computed tomography study. | cryptococcosis is a worldwide and potentially fatal mycosis documented in wild and captive koalas ( phascolarctos cinereus ) caused by cryptococcus neoformans . though mainly a subclinical disease, when the nasal cavity is affected, epistaxis, mucopurulent nasal discharge, dyspnea, and facial distortion may occur. this report describes a case of cryptococcosis in a koala where unilateral exophthalmos was the only evident clinical sign and magnetic resonance imaging and computed tomography findin ... | 2017 | 28363053 |
| cryptococcus lacticolor sp. nov. and rhodotorula oligophaga sp. nov., novel yeasts isolated from the nasal smear microbiota of queensland koalas kept in japanese zoological parks. | a total of 515 yeast strains were isolated from the nasal smears of queensland koalas and their breeding environments in japanese zoological parks between 2005 and 2012. the most frequent species in the basidiomycetous yeast biota isolated from koala nasal passages was cryptococcus neoformans, followed by rhodotorula minuta. r. minuta was the most frequent species in the breeding environments, while c. neoformans was rare. seven strains representing two novel yeast species were identified. analy ... | 2013 | 23653119 |