Publications

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towards a better understanding of the life cycle of trypanosoma copemani.trypanosoma copemani has been found infecting several threatened/endangered marsupial species within australia and is thought to be a key player in the rapid decline of the woylie (bettongia penicillata). to better understand the biology and life cycle of this parasite, the growth requirements, and kinetics of infection of two newly described genotypes, t. copemani g1 and g2, were investigated and compared with the t. cruzi strain-10r26 in vitro. both g1 and g2 were able to infect all four cell ...201626712388
in vitro drug susceptibility of two strains of the wildlife trypanosome, trypanosoma copemani: a comparison with trypanosoma cruzi.trypanosomes are blood protozoan parasites that are capable of producing illness in the vertebrate host. within australia, several native trypanosoma species have been described infecting wildlife. however, only trypanosoma copemani has been associated with pathological lesions in wildlife hosts and more recently has been associated with the drastic decline of the critically endangered woylie (bettongia penicillata). the impact that some trypanosomes have on the health of the vertebrate host has ...201728040568
trypanosomes of australian mammals: a review.approximately 306 species of terrestrial and arboreal mammals are known to have inhabited the mainland and coastal islands of australia at the time of european settlement in 1788. the exotic trypanosoma lewisi was the first mammalian trypanosome identified in australia in 1888, while the first native species, trypanosoma pteropi, was taxonomically described in 1913. since these discoveries, about 22% of the indigenous mammalian fauna have been examined during the surveillance of trypanosome biod ...201425161902
morphological and molecular characterization of trypanosoma copemani n. sp. (trypanosomatidae) isolated from gilbert's potoroo ( potorous gilbertii) and quokka ( setonix brachyurus).little is known of the prevalence and life-cycle of trypanosomes in mammals native to australia. native australian trypanosomes have previously been identified in marsupials in the eastern states of australia, with one recent report in brush-tailed bettongs (bettongia penicillata), or woylie in western australia in 2008. this study reports a novel trypanosoma sp. identified in blood smears, from 7 critically endangered gilbert's potoroos (potorous gilbertii) and 3 quokkas (setonix brachyurus) in ...200919416553
temporal and spatial dynamics of trypanosomes infecting the brush-tailed bettong (bettongia penicillata): a cautionary note of disease-induced population decline.the brush-tailed bettong or woylie (bettongia penicillata) is on the brink of extinction. its numbers have declined by 90% since 1999, with their current distribution occupying less than 1% of their former australian range. woylies are known to be infected with three different trypanosomes (trypanosoma vegrandis, trypanosoma copemani and trypanosoma sp. h25) and two different strains of t. copemani that vary in virulence. however, the role that these haemoparasites have played during the recent ...201424708757
trypanosomes genetic diversity, polyparasitism and the population decline of the critically endangered australian marsupial, the brush tailed bettong or woylie (bettongia penicillata).while much is known of the impact of trypanosomes on human and livestock health, trypanosomes in wildlife, although ubiquitous, have largely been considered to be non-pathogenic. we describe the genetic diversity, tissue tropism and potential pathogenicity of trypanosomes naturally infecting western australian marsupials. blood samples collected from 554 live-animals and 250 tissue samples extracted from 50 carcasses of sick-euthanized or road-killed animals, belonging to 10 species of marsupial ...201324533319
morphological polymorphism of trypanosoma copemani and description of the genetically diverse t. vegrandis sp. nov. from the critically endangered australian potoroid, the brush-tailed bettong (bettongia penicillata (gray, 1837)).the trypanosome diversity of the brush-tailed bettong (bettongia penicillata), known locally as the woylie, has been further investigated. at a species level, woylies are critically endangered and have declined by 90% since 1999. the predation of individuals made more vulnerable by disease is thought to be the primary cause of this decline, but remains to be proven.201323622560
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