| coexistence of different genotypes in the same bat and serological characterization of rousettus bat coronavirus hku9 belonging to a novel betacoronavirus subgroup. | rousettus bat coronavirus hku9 (ro-batcov hku9), a recently identified coronavirus of novel betacoronavirus subgroup d, from leschenault's rousette, was previously found to display marked sequence polymorphism among genomes of four strains. among 10 bats with complete rna-dependent rna polymerase (rdrp), spike (s), and nucleocapsid (n) genes sequenced, three and two sequence clades for all three genes were codetected in two and five bats, respectively, suggesting the coexistence of two or three ... | 2010 | 20702646 |
| a bat-derived putative cross-family recombinant coronavirus with a reovirus gene. | the emergence of severe acute respiratory syndrome coronavirus (sars-cov) in 2002 and middle east respiratory syndrome coronavirus (mers-cov) in 2012 has generated enormous interest in the biodiversity, genomics and cross-species transmission potential of coronaviruses, especially those from bats, the second most speciose order of mammals. herein, we identified a novel coronavirus, provisionally designated rousettus bat coronavirus gccdc1 (ro-batcov gccdc1), in the rectal swab samples of rousett ... | 2016 | 27676249 |
| sars-unique fold in the rousettus bat coronavirus hku9. | the coronavirus nonstructural protein 3 (nsp3) is a multifunctional protein that comprises multiple structural domains. this protein assists viral polyprotein cleavage, host immune interference, and may play other roles in genome replication or transcription. here, we report the solution nmr structure of a protein from the "sars-unique region" of the bat coronavirus hku9. the protein contains a frataxin fold or double-wing motif, which is an α + β fold that is associated with protein/protein int ... | 2017 | 28580734 |
| detection of recombinant rousettus bat coronavirus gccdc1 in lesser dawn bats (eonycteris spelaea) in singapore. | rousettus bat coronavirus gccdc1 (robat-cov gccdc1) is a cross-family recombinant coronavirus that has previously only been reported in wild-caught bats in yúnnan, china. we report the persistence of a related strain in a captive colony of lesser dawn bats captured in singapore. genomic evidence of the virus was detected using targeted enrichment sequencing, and further investigated using deeper, unbiased high throughput sequencing. robat-cov gccdc1 singapore shared 96.52% similarity with robat- ... | 2020 | 32422932 |