| experimental american leishmaniasis and chagas' disease in the brazilian squirrel monkey: effect of dual infection on antibodies to parasite antigens. | adult, laboratory-bred squirrel monkeys (saimiri sciureus) were infected with either leishmania braziliensis braziliensis or l. b. panamensis and, 42 weeks later, they were challenge-infected with trypanosoma cruzi. another group of monkeys was infected with t. cruzi and challenged with l. b. braziliensis after 42 weeks. immunoblotting was used to examine parasite antigens bound by antibodies in plasma obtained from the monkeys during the course of primary and challenge infections. during primar ... | 1991 | 1743848 |
| leishmania braziliensis in the squirrel monkey: development of primary and satellite lesions and lack of cross-immunity with leishmania donovani. | three female and 2 male adult laboratory-reared squirrel monkeys (saimiri sciureus) that previously had been inoculated with leishmania (leishmania) donovani and had recovered from experimental visceral leishmaniasis were each inoculated intradermally at the dorsal base of the tail with 2.2 x 10(7) culture-derived promastigotes of leishmania (viannia) panamensis. the progression and regression of subsequent lesions were examined for 36 wk in all 5 monkeys after which 3 of the monkeys were killed ... | 1990 | 2380874 |
| experimental american leishmaniasis in the brazilian squirrel monkey (saimiri sciureus): lesions, hematology, cellular, and humoral immune responses. | unulcerated cutaneous lesions appeared and persisted in squirrel monkeys experimentally infected with leishmania braziliensis braziliensis or l. b. panamensis. peripheral blood mononuclear cell (pbmc) numbers increased following infection, and cultured pbmcs from infected monkeys proliferated in response to parasite antigens. the responses of pbmcs to mitogens were not suppressed in infected monkeys. elevated levels of leishmania-specific immunoglobulins m and g were also observed. thus, the squ ... | 1987 | 3612761 |