| sero-epizootiologic survey of trypanosoma brucei in kenyan nonhuman primates. | blood samples were collected from 121 individuals of three species of wild-caught nonhuman primates from kenya, including african green monkeys (cercopithecus aethiops), syke's monkeys (c. mitis), and olive baboons (papio cynocephalus anubis), and were examined for circulating trypanosoma brucei and for t. brucei antigen and anti-trypanosome antibody. indirect antibody enzyme-linked immunosorbent assay detected titers of anti-t. brucei antibodies in 13 of the primates sampled, and field-oriented ... | 2002 | 12564531 |
| c-terminal mutants of apolipoprotein l-i efficiently kill both trypanosoma brucei brucei and trypanosoma brucei rhodesiense. | apolipoprotein l-i (apol1) is a human-specific serum protein that kills trypanosoma brucei through ionic pore formation in endosomal membranes of the parasite. the t. brucei subspecies rhodesiense and gambiense resist this lytic activity and can infect humans, causing sleeping sickness. in the case of t. b. rhodesiense, resistance to lysis involves interaction of the serum resistance-associated (sra) protein with the c-terminal helix of apol1. we undertook a mutational and deletional analysis of ... | 2009 | 19997494 |