| monkeys and rats are not susceptible to ferret hepatitis e virus infection. | ferret hepatitis e virus (hev), a novel hepatitis e-like virus, has been identified in ferrets in the netherlands, japan, and the us. to determine whether ferret hev transmits to other animals, we inoculated laboratory rats (wistar), nude rats (long-evans-rnu/rnu), and cynomolgus monkeys with ferret hev (f4351) by intravenous injection. none of the animals demonstrated a positive sign for virus replication, indicating that rats and monkeys are not susceptible to ferret hev. | 2015 | 25925280 |
| genetic and physicochemical analyses of a novel ferret hepatitis e virus, and clinical signs of infection after birth. | a novel cluster of five ferret hepatitis e virus (hev) strains was detected from nine laboratory ferrets (mustela putorius furo) imported from a ferret farm in the u.s. our detection of ferret hev rna and anti-hev antibodies, and alanine aminotransferase (alt) value assessment indicated that all of the 9 ferrets were infected with ferret hev, and that the infection exhibited three patterns: sub-clinical infection (n=2), acute hepatitis (n=6) and persistent infection (n=1). next-generation sequen ... | 2017 | 28347753 |