a virome sequencing approach to feline oral squamous cell carcinoma to evaluate viral causative factors. | feline oral squamous cell carcinoma (foscc) may be the best naturally-occurring model of human head and neck squamous cell carcinoma (hnscc). hnscc can be broadly divided into human papillomavirus (hpv)-negative cancers and hpv-positive cancers where hpv is the causative agent. previous studies in foscc have used both species-specific and species-nonspecific pcr primers that may be insensitive to the detection of pvs and other viruses that may be divergent from known sequences. virocap is a targ ... | 2020 | 31902496 |
identification of felis catus papillomavirus 3 in skin neoplasms from four cats. | bowenoid in situ carcinomas (biscs) are papillomavirus (pv)-induced skin neoplasms that are thought to be caused by felis catus papillomavirus (fcapv) 2. as biscs are typically multiple and can become extensive, they can be difficult to treat. herein we describe 4 cats that developed skin neoplasms that contained fcapv-3 dna. one cat developed multiple basal cell carcinomas (bccs), 1 a bisc with unusual extension into hair follicles, and 2 developed a single typical-appearing bisc. all neoplasms ... | 2018 | 29284382 |
genomic characterization of felis catus papillomavirus-3: a novel papillomavirus detected in a feline bowenoid in situ carcinoma. | there is increasing evidence that papillomaviruses (pvs) may cause skin cancer in cats. neoplasms most frequently contain felis domesticus pv type 2 (fdpv-2) dna, but other pv dna sequences have also been detected suggesting multiple pvs could cause disease. one of these sequences, fdpv-my2, was previously detected in 5 of a series of 70 feline skin cancers. the aim was to determine the genome sequence of this pv. using the circular nature of pv dna, 'outward facing' primers specific for fdpv-my ... | 2013 | 23639476 |
the detection of felis catus papillomavirus 3 dna in a feline bowenoid in situ carcinoma with novel histologic features and benign clinical behavior. | bowenoid in situ carcinoma (bisc; papillomavirus-associated squamous cell carcinoma in situ) is an uncommon skin neoplasm of cats that can result in euthanasia because of the development of multiple lesions or because of progression to invasive squamous cell carcinoma. biscs are currently thought to be caused by felis catus papillomavirus 2 (fcapv-2). the presently described cat developed a single 0.5 cm in diameter interscapular mass. over the following 18 months, the mass doubled in size; no a ... | 2016 | 27423734 |