| multilocus sequence analysis of borrelia bissettii strains from north america reveals a new borrelia species, borrelia kurtenbachii. | using multilocus sequence analyses (mlsa), we investigated the phylogenetic relationship of spirochaete strains from north america previously assigned to the genospecies borrelia bissettii. we amplified internal fragments of 8 housekeeping genes (clpa, clpx, nifs, pepx, pyrg, recg, rplb, and uvra) located on the main linear chromosome by polymerase chain reaction. phylogenetic analysis of concatenated sequences of the 8 loci showed that the b. bissettii clade consisted of 4 closely related clust ... | 2010 | 21157575 |
| the expanding lyme borrelia complex--clinical significance of genomic species? | ten years after the discovery of spirochaetes as agents of lyme disease in 1982 in the usa, three genomic species had diverged from the phenotypically heterogeneous strains of borrelia burgdorferi isolated in north america and europe: borrelia afzelii, b. burgdorferi sensu stricto (further b. burgdorferi), and borrelia garinii. whereas b. burgdorferi remained the only human pathogen in north america, all three species are aetiological agents of lyme borreliosis in europe. another seven genospeci ... | 2011 | 21414082 |
| investigation of genotypes of borrelia burgdorferi in ixodes scapularis ticks collected during surveillance in canada. | the genetic diversity of borrelia burgdorferi sensu stricto, the agent of lyme disease in north america, has consequences for the performance of serological diagnostic tests and disease severity. to investigate b. burgdorferi diversity in canada, where lyme disease is emerging, bacterial dna in 309 infected adult ixodes scapularis ticks collected in surveillance was characterized by multilocus sequence typing (mlst) and analysis of outer surface protein c gene (ospc) alleles. six ticks carried b ... | 2011 | 21421790 |
| borrelia kurtenbachii sp. nov., a widely distributed member of the borrelia burgdorferi sensu lato species complex in north america. | lyme borreliosis group spirochaetes are parasitic bacteria transmitted by vector ticks of the genus ixodes and distributed mainly between 40° and 60° northern latitudes. since borrelia burgdorferi sensu stricto (hereinafter, b. burgdorferi) was described in the north-eastern usa during the early 1980s, an increasing diversity has been noted within the species complex. here, we describe a novel genomic species, borrelia kurtenbachii sp. nov. (type strain 25015(t) = atcc baa-2495(t) = dsm 26572(t ... | 2014 | 24048870 |