| ball python nidovirus: a candidate etiologic agent for severe respiratory disease in python regius. | a severe, sometimes fatal respiratory disease has been observed in captive ball pythons (python regius) since the late 1990s. in order to better understand this disease and its etiology, we collected case and control samples and performed pathological and diagnostic analyses. electron micrographs revealed filamentous virus-like particles in lung epithelial cells of sick animals. diagnostic testing for known pathogens did not identify an etiologic agent, so unbiased metagenomic sequencing was per ... | 2014 | 25205093 |
| respiratory disease in ball pythons (python regius) experimentally infected with ball python nidovirus. | circumstantial evidence has linked a new group of nidoviruses with respiratory disease in pythons, lizards, and cattle. we conducted experimental infections in ball pythons (python regius) to test the hypothesis that ball python nidovirus (bpnv) infection results in respiratory disease. three ball pythons were inoculated orally and intratracheally with cell culture isolated bpnv and two were sham inoculated. antemortem choanal, oroesophageal, and cloacal swabs and postmortem tissues of infected ... | 2018 | 29329683 |
| discovery and partial genomic characterisation of a novel nidovirus associated with respiratory disease in wild shingleback lizards (tiliqua rugosa). | a respiratory disease syndrome has been observed in large numbers of wild shingleback lizards (tiliqua rugosa) admitted to wildlife care facilities in the perth metropolitan region of western australia. mortality rates are reportedly high without supportive treatment and care. here we used next generation sequencing techniques to screen affected and unaffected individuals admitted to kanyana wildlife rehabilitation centre in perth between april and december 2015, with the resultant discovery of ... | 2016 | 27828982 |